Thalidomide-5-propoxyethanamine
Thalidomide-5-propoxyethanamine is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
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- CAS. Nr.: 2357107-60-7
- Formel: C18H21N3O5
- Molecular Weight:359.38
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Alle E3 Ligase Ligand-Linker Conjugates Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
Beschreibung
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2357107-60-7
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Molecular Weight 359.38
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Formel C18H21N3O5
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SMILES
O=C1NC(C(CC1)N2C(C3=CC=C(CCCOCCN)C=C3C2=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Thalidomide-5-propoxyethanamine Related Classifications
HY-139544 Related Classifications
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