5690-03-9
5690-03-9
Chemical Structure
Splitomicin
Synonym(s): Splitomycin
- CAS No.: 5690-03-9
- Formula:C13H10O2
- Molecular Weight:198.22
IUPAC Name: 1,2-dihydro-3H-benzo[f]chromen-3-one
InChIKey: ISFPDBUKMJDAJH-UHFFFAOYSA-N
SMILES: O=C1CCC2=C3C=CC=CC3=CC=C2O1
Biological Activity: Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD+-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC50 of 60 μM[1].
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Splitomicin | 98.34% | Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD+-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC50 of 60 μM. | ||||||||||||||||||||
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Splitomicin (Standard) | ≥98% | Splitomicin (Standard) is the analytical standard of Splitomicin. This product is intended for research and analytical applications. Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD+-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC50 of 60 μM. | ||||||||||||||||||||
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