Fcgrt - Fc gamma receptor and transporter Gene
Also Known as FcRn
Species: Rattus norvegicus
Summary
Enables beta-2-microglobulin binding activity. Predicted to be involved in immune response. Predicted to be located in endosome membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human FCGRT (Fc fragment of IgG receptor and transporter). [provided by Alliance of Genome Resources, Apr 2022]
Fcgrt Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_033351.2 | NP_203502.1 | IgG receptor FcRn large subunit p51 precursor |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables beta-2-microglobulin binding |
IDA
IDA: Inferred from direct assay
|
2911353 | RGD |
| NOT enables peptide antigen binding |
IDA
IDA: Inferred from direct assay
|
9546397 | RGD |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
15598658 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
IgG receptor FcRn large subunit p51 |
|
|
Recombinant Fcgrt Proteins
| Cat. No. | Nom du produit | Accession | Pureté |
|---|---|---|---|
| HY-P75760 | FCGRT-B2M Heterodimer Protein, Rat (HEK293, His, solution) | P13599 (A23-S298)&P07151 (I21-M119) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P75761 | FCGRT-B2M Heterodimer Protein, Rat (Biotinylated, HEK293, His) | P13599 (A23-S298)&P07151 (I21-M119) | ≥ 85%, as determined by reducing SDS-PAGE. |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Homo sapiens | Fcgrt | NCBI | NCBI:2217 |
| Macaca fascicularis | Fcgrt | NCBI | NCBI:102128913 |
| Canis lupus familiaris | Fcgrt | NCBI | |
| Mus musculus | Fcgrt | NCBI | NCBI:14132 |
| Leporidae | Fcgrt | NCBI |