Chlorotris(triphenylphosphine)copper  (Synonyms: CuCl(TPP)3)

Chlorotris(triphenylphosphine)copper (CuCl(TPP)₃) is a DNA-targeted metal complex. Chlorotris(triphenylphosphine)copper involves non-covalent interactions (such as groove binding mode) through the copper(I) center to affect DNA function, showing inhibitory activity against bacteria, fungi, and tumor cells. Chlorotris(triphenylphosphine)copper is promising for research of antibacterial, antitumor, and antioxidant agents^[1].

885.86

C₅₄H₄₅ClCuP₃

15709-76-9

Solid

White to off-white

[Cl-][Cu+]([P](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)([P](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)[P](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9

Room temperature in continental US; may vary elsewhere.

RT, protect from light

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

• [1]. Khan S I, et al. Mononuclear copper (I) complexes with triphenylphosphine and N, N′-disubstituted thioureas: synthesis, characterization, and biological evaluation[J]. Journal of Coordination Chemistry, 2018, 71(24): 4086-4108.