Cholic acid 3-O-glucuronide disodium
Based on 1 Customer Validation
Cholic acid 3-O-glucuronide (OCA-3-glucuronide) disodium is a farnesoid X receptor (FXR) agonist with an EC50 value of 91.5 μM. Cholic acid 3-O-glucuronide is promising for research of bile acid metabolism and detoxification.
For research use only. We do not sell to patients.
- CAS No.: 59274-69-0
- Formula: C30H46Na2O11
- Molecular Weight:628.66
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 59274-69-0
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Appearance Solid
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Molecular Weight 628.66
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Formula C30H46Na2O11
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Color White to off-white
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SMILES
O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(O[Na])=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O[Na])=O)([H])C1)C)O)C
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Synonyms
OCA-3-glucuronide disodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Mostarda S, et al. Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification. Eur J Med Chem. 2018 Jan 20;144:349-358. [Content Brief]
[2]. Mach S, et al. Metabolism of obeticholic acid in brown bullhead (Ameiurus nebulosus). Environ Sci Pollut Res Int. 2019 Jul;26(20):20316-20324. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)