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  3. Cinacalcet impurity 1 hydrochloride

Cinacalcet impurity 1 hydrochloride is an impurity of Cinacalcet (HY-70037).

For research use only. We do not sell to patients.

Cinacalcet impurity 1 hydrochloride

Cinacalcet impurity 1 hydrochloride Chemical Structure

CAS No. : 1229225-42-6

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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Description

Cinacalcet impurity 1 hydrochloride is an impurity of Cinacalcet (HY-70037).

Molecular Weight

365.82

Formula

C20H19ClF3N

CAS No.
Appearance

Solid

Color

Gray to dark gray

SMILES

C[C@@]([H])(NCC1=CC=CC(C(F)(F)F)=C1)C2=CC=CC3=C2C=CC=C3.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (68.34 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7336 mL 13.6679 mL 27.3358 mL
5 mM 0.5467 mL 2.7336 mL 5.4672 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7336 mL 13.6679 mL 27.3358 mL 68.3396 mL
5 mM 0.5467 mL 2.7336 mL 5.4672 mL 13.6679 mL
10 mM 0.2734 mL 1.3668 mL 2.7336 mL 6.8340 mL
15 mM 0.1822 mL 0.9112 mL 1.8224 mL 4.5560 mL
20 mM 0.1367 mL 0.6834 mL 1.3668 mL 3.4170 mL
25 mM 0.1093 mL 0.5467 mL 1.0934 mL 2.7336 mL
30 mM 0.0911 mL 0.4556 mL 0.9112 mL 2.2780 mL
40 mM 0.0683 mL 0.3417 mL 0.6834 mL 1.7085 mL
50 mM 0.0547 mL 0.2734 mL 0.5467 mL 1.3668 mL
60 mM 0.0456 mL 0.2278 mL 0.4556 mL 1.1390 mL
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Cinacalcet impurity 1 hydrochloride Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cinacalcet impurity 1 hydrochloride
Cat. No.:
HY-I0577A
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