1. Peptides
  2. Connexin mimetic peptide 40,37GAP26

Connexin mimetic peptide 40,37GAP26 is a biological active peptide. (This peptide corresponds to the GAP26 domain of the extracellular loop of the major vascular connexins (Cx37, Cx40), designated as 37, 40Gap 26 according to Cx homology. It was used to investigate the role of gap junctions in the spread of endothelial hyperpolarizations evoked by cyclopiazonic acid (CPA) through the wall of the rodent iliac artery. The gap junction plaques constructed from Cx37 and Cx40 were abundant in the endothelium. This peptide provides inhibitory effects against subintimal hyperpolarization.)

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Connexin mimetic peptide 40,37GAP26 Chemical Structure

Connexin mimetic peptide 40,37GAP26 Chemical Structure

CAS No. : 514787-21-4

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Description

Connexin mimetic peptide 40,37GAP26 is a biological active peptide. (This peptide corresponds to the GAP26 domain of the extracellular loop of the major vascular connexins (Cx37, Cx40), designated as 37, 40Gap 26 according to Cx homology. It was used to investigate the role of gap junctions in the spread of endothelial hyperpolarizations evoked by cyclopiazonic acid (CPA) through the wall of the rodent iliac artery. The gap junction plaques constructed from Cx37 and Cx40 were abundant in the endothelium. This peptide provides inhibitory effects against subintimal hyperpolarization.)

Molecular Weight

1548.76

Formula

C70H105N19O19S

CAS No.
Sequence

Val-Cys-Tyr-Asp-Gln-Ala-Phe-Pro-Ile-Ser-His-Ile-Arg

Sequence Shortening

VCYDQAFPISHIR

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Connexin mimetic peptide 40,37GAP26
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HY-P5387
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