1. Immunology/Inflammation
  2. COX
  3. COX-2-IN-7

COX-2-IN-7 (compound 4a) is a potent, selective, and orally active inhibitor of COX-2 with an IC50 of 6.585 uM. COX-2-IN-7 has higher COX-2 selectivity than Celecoxib. COX-2-IN-7 shows good in vivo anti-inflammatory and low ulcerogenic activity.

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COX-2-IN-7

COX-2-IN-7 Estructura química

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Descripciòn

COX-2-IN-7 (compound 4a) is a potent, selective, and orally active inhibitor of COX-2 with an IC50 of 6.585 uM. COX-2-IN-7 has higher COX-2 selectivity than Celecoxib. COX-2-IN-7 shows good in vivo anti-inflammatory and low ulcerogenic activity[1].

Peso molecular

331.41

Fòrmula

C15H13N3O2S2

SMILES

CS(=O)(C1=CC=C(C=C1)N2N=C(N=C2C3=CC=CC=C3)S)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
COX-2-IN-7
Cat. No.:
HY-115934
Cantidad:
MCE Japan Authorized Agent: