Delapril-d3 hydrochloride
Delapril-d3 (hydrochloride) is the deuterium labeled Delapril hydrochloride. Delapril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor for the treatment of cardiovascular diseases.
For research use only. We do not sell to patients.
- CAS No.: 2714473-25-1
- Formula: C26H30D3ClN2O5
- Molecular Weight:492.02
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2714473-25-1
-
Unlabeled Cas 83435-67-0
-
Molecular Weight 492.02
-
Formula C26H30D3ClN2O5
-
SMILES
CCOC([C@H](CCC1=CC=CC=C1)N[C@@H](C)C(N(C2([2H])CC3=C(C=CC=C3)C2)C([2H])([2H])C(O)=O)=O)=O.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Razzetti R, et al. Pharmacokinetic and pharmacologic properties of delapril, a lipophilic nonsulfhydryl angiotensin-converting enzyme inhibitor. Am J Cardiol. 1995 Jun 16;75(18):7F-12F. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)