Delta (Phospho) Sleep Inducing Peptide
Based on 1 Customer Validation
Delta (Phospho) Sleep Inducing Peptide (DSIP-P) is a long-lasting sleep-promoting peptide. Delta (Phospho) Sleep Inducing Peptide induces changes in the circadian locomotor behavior in rats.
For research use only. We do not sell to patients.
- Purity: 99.01%
- CAS No.: 70754-23-3
- Formula: C35H49N10O18P
- Molecular Weight:928.79
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Delta (Phospho) Sleep Inducing Peptide (20-300 nM) increases rat pineal N-acetyltransferase (NAT) activity induced by norepinephrine in vitro[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female rats from own inbred strain (KBS/K60)[1]
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Dosage:0.1 nmol/kg
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Administration:Intravenous injection; once daily for 4 consecutive days
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Result:Induced rapid and mark changes in the circadian locomotor behavior when during the light (sleeping) phase testing animals became relatively more active.
Chemical Information
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CAS No. 70754-23-3
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Appearance Solid
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Molecular Weight 928.79
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Formula C35H49N10O18P
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Color White to off-white
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Synonyms
DSIP-P
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Sequence
Trp-Ala-Gly-Gly-Asp-Ala-{Ser(PO3H2)}-Gly-Glu
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Sequence Shortening
WAGGDA-{Ser(PO3H2)}-GE
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (262 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Graf M, et al. Effects of repeated DSIP and DSIP-P administration on the circadian locomotor activity of rats. Pharmacol Biochem Behav. 1981 Nov;15(5):717-21. [Content Brief]
[2]. Nakagaki K, et al. Sleep-promoting effect following intracerebroventricular injection of a phosphorylated analogue of delta sleep-inducing peptide (DSIP-P) in rats. Neurosci Lett. 1988 Aug 31;91(2):160-4. [Content Brief]
[3]. Graf MV, Schoenenberger GA. Delta sleep-inducing peptide modulates the stimulation of rat pineal N-acetyltransferase activity by involving the alpha 1-adrenergic receptor. J Neurochem. 1987 Apr;48(4):1252-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Delta (Phospho) Sleep Inducing Peptide Related Classifications
HY-P3819 Related Classifications
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