1. PROTAC
  2. PROTAC
    Ligand for E3 Ligase
  3. E3 ligase Ligand 8 hydrochloride

E3 ligase Ligand 8 hydrochloride 

Cat. No.: HY-115446A Purity: 98.24%
Handling Instructions

E3 ligase Ligand 8 hydrochloride (compound 24) is a Ligand of BET for E3 Ligase used in PROTAC, with IC50 values of 0.98 nM and 13.7 nM in RS4;11 and MOLM-13 cells, respectively.

For research use only. We do not sell to patients.

E3 ligase Ligand 8 hydrochloride Chemical Structure

E3 ligase Ligand 8 hydrochloride Chemical Structure

Size Price Stock Quantity
100 mg USD 450 In-stock
Estimated Time of Arrival: December 31
500 mg USD 1450 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Description

E3 ligase Ligand 8 hydrochloride (compound 24) is a Ligand of BET for E3 Ligase used in PROTAC, with IC50 values of 0.98 nM and 13.7 nM in RS4;11 and MOLM-13 cells, respectively[1].

IC50 & Target

E3 ligase[1].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

351.83

Formula

C₁₇H₂₂ClN₃O₃

SMILES

O=C(C(N(CC1=C2C=CC=C1CCCCN)C2=O)CC3)NC3=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
E3 ligase Ligand 8 hydrochloride
Cat. No.:
HY-115446A
Quantity:

E3 ligase Ligand 8 hydrochloride

Cat. No.: HY-115446A