Edivoxetine hydrochloride
Based on 1 Customer Validation
Edivoxetine (LY 2216684) hydrochloride is a potent and selective norepinephrine reuptake inhibitor. Edivoxetine hydrochloride can be used for the study of major depressive disorder (MDD) and attention-deficit/hyperactivity disorder (ADHD).
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 1194374-05-4
- Formula: C18H27ClFNO4
- Molecular Weight:375.86
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Biological Activity
Chemical Information
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CAS No. 1194374-05-4
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Appearance Solid
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Molecular Weight 375.86
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Formula C18H27ClFNO4
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Color White to off-white
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SMILES
COC(C=CC(F)=C1)=C1C[C@@](C2CCOCC2)([C@]3([H])CNCCO3)O.Cl
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Synonyms
LY 2216684 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (332.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
[1]. Jin L,et al. Clinical outcomes from an opeJin L, Xu W, Krefetz D, et al. Clinical outcomes from an open-label study of edivoxetine use in pediatric patients with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2013;23(3):200-207 [Content Brief]
[2]. Kielbasa W, et al. The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor. Eur J Clin Pharmacol. 2013;69(12):2011-2019. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6606 mL | 13.3028 mL | 26.6057 mL | 66.5141 mL |
| 5 mM | 0.5321 mL | 2.6606 mL | 5.3211 mL | 13.3028 mL | |
| 10 mM | 0.2661 mL | 1.3303 mL | 2.6606 mL | 6.6514 mL | |
| 15 mM | 0.1774 mL | 0.8869 mL | 1.7737 mL | 4.4343 mL | |
| 20 mM | 0.1330 mL | 0.6651 mL | 1.3303 mL | 3.3257 mL | |
| 25 mM | 0.1064 mL | 0.5321 mL | 1.0642 mL | 2.6606 mL | |
| 30 mM | 0.0887 mL | 0.4434 mL | 0.8869 mL | 2.2171 mL | |
| 40 mM | 0.0665 mL | 0.3326 mL | 0.6651 mL | 1.6629 mL | |
| 50 mM | 0.0532 mL | 0.2661 mL | 0.5321 mL | 1.3303 mL | |
| 60 mM | 0.0443 mL | 0.2217 mL | 0.4434 mL | 1.1086 mL | |
| 80 mM | 0.0333 mL | 0.1663 mL | 0.3326 mL | 0.8314 mL | |
| 100 mM | 0.0266 mL | 0.1330 mL | 0.2661 mL | 0.6651 mL |
Edivoxetine hydrochloride Related Classifications
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