EGFR/VEGFR2-IN-5
EGFR/VEGFR2-IN-5 (Compound 14) is an orally active dual inhibitor of EGFR and VEGFR2 with an IC50 value of 1.15 µM for VEGFR2 and an IC50 value of 0.28 μM for EGFRT790M. EGFR/VEGFR2-IN-5 has significant anticancer activity.
For research use only. We do not sell to patients.
- Formula: C17H15N7O5S
- Molecular Weight:429.41
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
EGFRT790M 0.28 μM (IC50) |
VEGFR-2 1.15 μM (IC50) |
Chemical Information
-
Molecular Weight 429.41
-
Formula C17H15N7O5S
-
SMILES
O=C(O)C1=CC=CC=C1/N=N/C2C(NC(NS(=O)(C3=CC=C(N)C=C3)=O)=NC2=N)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)