1. MAPK/ERK Pathway Stem Cell/Wnt
  2. ERK
  3. ERK2-IN-3

ERK2-IN-3 (compound 2) is a inhibitor of ERK2, and inhibits Erk2WT and Erk2DS1 activation loop phosphorylation, with IC50 of 5 μM and 42 nM, respectively.

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ERK2-IN-3

ERK2-IN-3 Estructura química

No. CAS : 1415050-57-5

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Descripciòn

ERK2-IN-3 (compound 2) is a inhibitor of ERK2, and inhibits Erk2WT and Erk2DS1 activation loop phosphorylation, with IC50 of 5 μM and 42 nM, respectively[1].

IC50 & Target

5 μM and 42 nM(Erk2WT and Erk2DS1[1].

Peso molecular

462.47

Fòrmula

C26H21F3N4O

No. CAS
SMILES

CC1=CC=C(NC(C2=CC=CC(C(F)(F)F)=C2)=O)C=C1C3=CC=C4C(C=NC(NC5CC5)=N4)=C3

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
ERK2-IN-3
Cat. No.:
HY-18849
Cantidad:
MCE Japan Authorized Agent: