1415050-57-5
1415050-57-5
Chemical Structure
ERK2-IN-3
- CAS No.: 1415050-57-5
- Formula:C26H21F3N4O
- Molecular Weight:462.47
IUPAC Name: N-(3-(2-(cyclopropylamino)quinazolin-6-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
InChIKey: BYBFDHQBBWQPTD-UHFFFAOYSA-N
SMILES: CC1=CC=C(NC(C2=CC=CC(C(F)(F)F)=C2)=O)C=C1C3=CC=C4C(C=NC(NC5CC5)=N4)=C3
Biological Activity: ERK2-IN-3 (compound 2) is a inhibitor of ERK2, and inhibits Erk2WT and Erk2DS1 activation loop phosphorylation, with IC50 of 5 μM and 42 nM, respectively[1].
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ERK2-IN-3 | ERK2-IN-3 (compound 2) is a inhibitor of ERK2, and inhibits Erk2WT and Erk2DS1 activation loop phosphorylation, with IC50 of 5 μM and 42 nM, respectively. | |||||||||||||||||||||
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References
Keywords
