1613410-75-5
1613410-75-5
Chemical Structure
N19-0881
- CAS No.: 1613410-75-5
- Formula:C17H14ClN3O3
- Molecular Weight:343.76
IUPAC Name: 2-(5-((4-chloro-2-methylbenzyl)oxy)-1H-pyrazol-1-yl)isonicotinic acid
InChIKey: PSOBPHXKKHPWMU-UHFFFAOYSA-N
SMILES: O=C(C1=CC(N2N=CC=C2OCC3=CC=C(Cl)C=C3C)=NC=C1)O
Biological Activity: N19-0881 (Compound 33) is an orally active, potent and selective KDM5A/5B histone lysine demethylase inhibitor (IC50= 0.013 μM and 0.002 μM, respectively). N19-0881 is promising for research of epigenetically dysregulated tumors (e.g., breast cancer)[1].
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N19-0881 | N19-0881 (Compound 33) is an orally active, potent and selective KDM5A/5B histone lysine demethylase inhibitor (IC50= 0.013 μM and 0.002 μM, respectively). N19-0881 is promising for research of epigenetically dysregulated tumors (e.g., breast cancer). | |||||||||||||||||||||
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