86227-47-6
Chemical Structure
Eicosapentaenoic acid ethyl ester
Synonym(s): EPA ethyl ester; Ethyl eicosapentaenoate; AMR101
- CAS No.: 86227-47-6
- Formula:C22H34O2
- Molecular Weight:330.50
IUPAC Name: ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
InChIKey: SSQPWTVBQMWLSZ-AAQCHOMXSA-N
SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCC)=O
Biological Activity: Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Eicosapentaenoic acid ethyl ester | 98.0% | Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats. | ||||||||||||||||||||
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Eicosapentaenoic acid ethyl ester (Standard) | ≥98% | Eicosapentaenoic acid ethyl ester (Standard) is the analytical standard of Eicosapentaenoic acid ethyl ester. This product is intended for research and analytical applications. Eicosapentaenoic acid ethyl ester is an omega-3 fatty acid agent. | ||||||||||||||||||||
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Eicosapentaenoic acid ethyl ester-d5 | Eicosapentaenoic acid ethyl ester-d5 is the deuterium labeled Eicosapentaenoic acid ethyl ester. Eicosapentaenoic acid ethyl ester is an omega-3 fatty acid agent. | |||||||||||||||||||||
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Eicosapentaenoic acid ethyl ester-d5-1 | Eicosapentaenoic acid ethyl ester-d5-1 (EPA ethyl ester-d5) is deuterium labeled Eicosapentaenoic acid ethyl ester. | |||||||||||||||||||||
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References
- [1]. Jacobson TA. A new pure ω-3 eicosapentaenoic acid ethyl ester (AMR101) for the management of hypertriglyceridemia: the MARINE trial. Expert Rev Cardiovasc Ther. 2012 Jun;10(6):687-695. [Content Brief]
- [2]. Makino M, et al. Effect of eicosapentaenoic acid ethyl ester on hypothyroid function. J Endocrinol. 2001 Nov;171(2):259-65. [Content Brief]
- [3]. Pérez-Echarri N, et al. Down-regulation in muscle and liver lipogenic genes: EPA ethyl ester treatment in lean and overweight (high-fat-fed) rats. J Nutr Biochem. 2009 Sep;20(9):705-14. [Content Brief]
