86630-46-8
86630-46-8
Chemical Structure
Nudol
- CAS No.: 86630-46-8
- Formula:C16H14O4
- Molecular Weight:270.28
IUPAC Name: 3,4-dimethoxyphenanthrene-2,7-diol
InChIKey: JZIYNZGPIKGKQC-UHFFFAOYSA-N
SMILES: OC1=C(OC)C(OC)=C2C3=CC=C(O)C=C3C=CC2=C1
Biological Activity: Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nudol | 99.60% | Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma. | ||||||||||||||||||||
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References
- [1]. Yuying Zhang, et al. Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells. Drug Des Devel Ther. 2019 Jul 29;13:2591-2601. [Content Brief]
- [2]. Mohammad Al-Amin, et al. Inhibitory Effect of Dioscorea bulbifera Tubers on the Migration of Triple-Negative Breast Cancer Cells. Breast Cancer Cells. Rev. Bras. Farmacogn. 31, 335–341 (2021).
