1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. FGFR-IN-6

FGFR-IN-6 (Compound 5) is a FGFR inhibitor. FGFR-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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FGFR-IN-6

FGFR-IN-6 화학구조

CAS No. : 2762955-18-8

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제품 설명

FGFR-IN-6 (Compound 5) is a FGFR inhibitor[1]. FGFR-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

In Vitro

FGFR-IN-6 (Compound 5) shows antiproliferation activity with IC50 values of 0.5-5 nM against BaF3-Tel-FGFR2WT and various mutant FGFR2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

430.46

화학식

C23H22N6O3

CAS No.
SMILES

C=CC(N1CC[C@@H](C1)N2N=C(C(C(N)=O)=C2N)C#CC3=CC4=C(OC(C5CC5)=N4)C=C3)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
FGFR-IN-6
Cat. No.:
HY-147621
수량:
MCE Japan Authorized Agent: