Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH

Name: Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH
Brand: MedChemExpress
SKU: HY-P10929
Rating: 4.5 (0 reviews)

Cat. No.: HY-P10929 Purity: 99.31%: Data Sheet
COA

SDS
Handling Instructions
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Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH is a drug intermediate in the synthesis of Tirzepatide. Tirzepatide is a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor (GLP-1R) agonist.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH Chemical Structure

CAS No. : 2460751-66-8

Size	Stock	Quantity
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Purity & Documentation
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Description

In Vitro

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH has important value in proteomics research and solid-phase peptide synthesis. The Fmoc protecting group is typically cleaved using a base, an orthogonal deprotection strategy different from that of the acid-sensitive Boc group.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1224.56

Formula

C₆₆H₁₀₅N₅O₁₆

CAS No.

2460751-66-8

Appearance

Oil

Color

Colorless to light yellow

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Pure form	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (163.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.8166 mL	4.0831 mL	8.1662 mL
5 mM	0.1633 mL	0.8166 mL	1.6332 mL
10 mM	0.0817 mL	0.4083 mL	0.8166 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.31%

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Data Sheet (265 KB) SDS (254 KB)

COA (240 KB) RP-HPLC (305 KB) MS (74 KB)

Handling Instructions (2659 KB)

References

[1]. Karagiannis T, Aet al. Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis. Diabetologia. 2022 Aug;65(8):1251-1261. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.8166 mL	4.0831 mL	8.1662 mL	20.4155 mL
	5 mM	0.1633 mL	0.8166 mL	1.6332 mL	4.0831 mL
	10 mM	0.0817 mL	0.4083 mL	0.8166 mL	2.0415 mL
	15 mM	0.0544 mL	0.2722 mL	0.5444 mL	1.3610 mL
	20 mM	0.0408 mL	0.2042 mL	0.4083 mL	1.0208 mL
	25 mM	0.0327 mL	0.1633 mL	0.3266 mL	0.8166 mL
	30 mM	0.0272 mL	0.1361 mL	0.2722 mL	0.6805 mL
	40 mM	0.0204 mL	0.1021 mL	0.2042 mL	0.5104 mL
	50 mM	0.0163 mL	0.0817 mL	0.1633 mL	0.4083 mL
	60 mM	0.0136 mL	0.0681 mL	0.1361 mL	0.3403 mL
	80 mM	0.0102 mL	0.0510 mL	0.1021 mL	0.2552 mL
	100 mM	0.0082 mL	0.0408 mL	0.0817 mL	0.2042 mL