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  3. Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH 

Cat. No.: HY-P10929 Purity: 99.31%
Handling Instructions Technical Support

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH is a drug intermediate in the synthesis of Tirzepatide. Tirzepatide is a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor (GLP-1R) agonist.

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Custom Peptide Synthesis

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH 화학구조

CAS No. : 2460751-66-8

사이즈 가격 재고 수량
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

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제품 설명

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH is a drug intermediate in the synthesis of Tirzepatide. Tirzepatide is a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor (GLP-1R) agonist[1].

In Vitro

Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH has important value in proteomics research and solid-phase peptide synthesis. The Fmoc protecting group is typically cleaved using a base, an orthogonal deprotection strategy different from that of the acid-sensitive Boc group.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

1224.56

화학식

C66H105N5O16

CAS No.
Appearance

Oil

Color

Colorless to light yellow

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture

Pure form -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

DMSO : 200 mg/mL (163.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8166 mL 4.0831 mL 8.1662 mL
5 mM 0.1633 mL 0.8166 mL 1.6332 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 99.31%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8166 mL 4.0831 mL 8.1662 mL 20.4155 mL
5 mM 0.1633 mL 0.8166 mL 1.6332 mL 4.0831 mL
10 mM 0.0817 mL 0.4083 mL 0.8166 mL 2.0415 mL
15 mM 0.0544 mL 0.2722 mL 0.5444 mL 1.3610 mL
20 mM 0.0408 mL 0.2042 mL 0.4083 mL 1.0208 mL
25 mM 0.0327 mL 0.1633 mL 0.3266 mL 0.8166 mL
30 mM 0.0272 mL 0.1361 mL 0.2722 mL 0.6805 mL
40 mM 0.0204 mL 0.1021 mL 0.2042 mL 0.5104 mL
50 mM 0.0163 mL 0.0817 mL 0.1633 mL 0.4083 mL
60 mM 0.0136 mL 0.0681 mL 0.1361 mL 0.3403 mL
80 mM 0.0102 mL 0.0510 mL 0.1021 mL 0.2552 mL
100 mM 0.0082 mL 0.0408 mL 0.0817 mL 0.2042 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH
Cat. No.:
HY-P10929
수량:
MCE Japan Authorized Agent: