Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH
Based on 1 Customer Validation
Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH is a drug intermediate in the synthesis of Tirzepatide. Tirzepatide is a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor (GLP-1R) agonist.
For research use only. We do not sell to patients.
- Purity : 99.31%
- CAS No.: 2460751-66-8
- Formula: C66H105N5O16
- Molecular Weight:1224.56
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Storage:
Sealed storage, away from moisture.
Pure form -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
In Vitro
Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH has important value in proteomics research and solid-phase peptide synthesis. The Fmoc protecting group is typically cleaved using a base, an orthogonal deprotection strategy different from that of the acid-sensitive Boc group.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2460751-66-8
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Appearance Oil
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Molecular Weight 1224.56
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Formula C66H105N5O16
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Color Colorless to light yellow
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Pure form -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 200 mg/mL (163.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8166 mL | 4.0831 mL | 8.1662 mL | 20.4155 mL |
| 5 mM | 0.1633 mL | 0.8166 mL | 1.6332 mL | 4.0831 mL | |
| 10 mM | 0.0817 mL | 0.4083 mL | 0.8166 mL | 2.0415 mL | |
| 15 mM | 0.0544 mL | 0.2722 mL | 0.5444 mL | 1.3610 mL | |
| 20 mM | 0.0408 mL | 0.2042 mL | 0.4083 mL | 1.0208 mL | |
| 25 mM | 0.0327 mL | 0.1633 mL | 0.3266 mL | 0.8166 mL | |
| 30 mM | 0.0272 mL | 0.1361 mL | 0.2722 mL | 0.6805 mL | |
| 40 mM | 0.0204 mL | 0.1021 mL | 0.2042 mL | 0.5104 mL | |
| 50 mM | 0.0163 mL | 0.0817 mL | 0.1633 mL | 0.4083 mL | |
| 60 mM | 0.0136 mL | 0.0681 mL | 0.1361 mL | 0.3403 mL | |
| 80 mM | 0.0102 mL | 0.0510 mL | 0.1021 mL | 0.2552 mL | |
| 100 mM | 0.0082 mL | 0.0408 mL | 0.0817 mL | 0.2042 mL |