4224-84-4
4224-84-4
Chemical Structure
hCAIX/XII-IN-12
- CAS No.: 4224-84-4
- Formula:C11H7BrO4
- Molecular Weight:283.07
InChIKey: CZVCQXLWYJTEDA-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(O)=C1C(C)=O)C=C(Br)C=C2
Biological Activity: hCAIX/XII-IN-12 (Compound 6) is a potent and highly selective dual inhibitor of hCA IX and hCA XII, with Ki values of 8.2 and 5.6 nM respectively. hCAIX/XII-IN-12 exhibits significant anti-proliferative activity against colon cancer cells, and this activity remains effective under hypoxic conditions. hCAIX/XII-IN-12 can be used for research on colon cancer[1].
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hCAIX/XII-IN-12 | hCAIX/XII-IN-12 (Compound 6) is a potent and highly selective dual inhibitor of hCA IX and hCA XII, with Ki values of 8.2 and 5.6 nM respectively. hCAIX/XII-IN-12 exhibits significant anti-proliferative activity against colon cancer cells, and this activity remains effective under hypoxic conditions. hCAIX/XII-IN-12 can be used for research on colon cancer. | |||||||||||||||||||||
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