hCAIX/XII-IN-12
hCAIX/XII-IN-12 (Compound 6) is a potent and highly selective dual inhibitor of hCA IX and hCA XII, with Ki values of 8.2 and 5.6 nM respectively. hCAIX/XII-IN-12 exhibits significant anti-proliferative activity against colon cancer cells, and this activity remains effective under hypoxic conditions. hCAIX/XII-IN-12 can be used for research on colon cancer.
For research use only. We do not sell to patients.
- CAS No.: 4224-84-4
- Formula: C11H7BrO4
- Molecular Weight:283.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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hCA IX 8.2 nM (Ki) |
hCA XII 5.6 nM (Ki) |
Chemical Information
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CAS No. 4224-84-4
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Molecular Weight 283.07
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Formula C11H7BrO4
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SMILES
O=C1OC2=C(C(O)=C1C(C)=O)C=C(Br)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)