AIG1 - androgen induced 1 Gene

Also Known as AIG-1; dJ95L4.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51390

About AIG1

Cytogenetic location: 6q24.2 Genomic coordinates (GRCh38): 6:143,059,213-143,343,883 (from NCBI)

This gene has 10 transcripts (splice variants), 207 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 13.8), kidney (RPKM 9.3) and 24 other tissues.

Summary

Enables hydrolase activity. Involved in long-chain fatty acid catabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

AIG1 Products (24)

mRNA Protein Name
NM_001286587.2 NP_001273516.1 androgen-induced gene 1 protein isoform b
NM_001286588.2 NP_001273517.1 androgen-induced gene 1 protein isoform c
NM_001286589.2 NP_001273518.1 androgen-induced gene 1 protein isoform d
NM_001363721.2 NP_001350650.1 androgen-induced gene 1 protein isoform e
NM_001366344.1 NP_001353273.1 androgen-induced gene 1 protein isoform f precursor
NM_001366345.1 NP_001353274.1 androgen-induced gene 1 protein isoform g
NM_001366346.1 NP_001353275.1 androgen-induced gene 1 protein isoform h
NM_001366347.1 NP_001353276.1 androgen-induced gene 1 protein isoform i
NM_001366348.1 NP_001353277.1 androgen-induced gene 1 protein isoform j
NM_001366349.2 NP_001353278.1 androgen-induced gene 1 protein isoform k
NM_001366350.1 NP_001353279.1 androgen-induced gene 1 protein isoform l
NM_001366351.1 NP_001353280.1 androgen-induced gene 1 protein isoform m
NM_001366352.1 NP_001353281.1 androgen-induced gene 1 protein isoform n
NM_001366353.1 NP_001353282.1 androgen-induced gene 1 protein isoform o
NM_001366354.1 NP_001353283.1 androgen-induced gene 1 protein isoform p
NM_001366355.1 NP_001353284.1 androgen-induced gene 1 protein isoform q
NM_001366356.2 NP_001353285.1 androgen-induced gene 1 protein isoform r precursor
NM_001366357.1 NP_001353286.1 androgen-induced gene 1 protein isoform s
NM_001366358.1 NP_001353287.1 androgen-induced gene 1 protein isoform t
NM_001366359.2 NP_001353288.1 androgen-induced gene 1 protein isoform u
NM_001366361.1 NP_001353290.1 androgen-induced gene 1 protein isoform v
NM_001366362.1 NP_001353291.1 androgen-induced gene 1 protein isoform w
NM_001366363.1 NP_001353292.1 androgen-induced gene 1 protein isoform x precursor
NM_016108.4 NP_057192.2 androgen-induced gene 1 protein isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables hydrolase activity IMP
IMP: Inferred from mutant phenotype
27018888 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21988832 GOA
Biological Process GO Annotation Evidence Referencias Source
involved in long-chain fatty acid catabolic process IMP
IMP: Inferred from mutant phenotype
27018888 GOA
Cellular Component GO Annotation Evidence Referencias Source
located in membrane IDA
IDA: Inferred from direct assay
27018888 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AIG1 Protein Structure

Far-17a_AIG1

Far-17a_AIG1: FAR-17a/AIG1-like protein (13 - 219)

  • 0
  • 100
  • 200
  • 245 a.a.
Protein Preferred Names Protein Names

androgen-induced gene 1 protein

  • FAHFA hydrolase AIG1

AIG1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Referencias
Intra
AIG1 Q9NVV5 RCHY1 Homo sapiens Q96PM5
Confocal
21988832
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Amebiasis

  • Amoebiasis

  • Entamoebiasis

  • Chronic Intestinal Amebiasis

  • Amoebiasis, Unspecified

  • Amebic Colitis

  • Amoebic Enteritis

  • Infection Due To Entamoeba Histolytica

  • Amoebic Infection

  • Disease Due To Endamoebidae

  • Amoebiasis Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-116895 JJH260 Inhibitor 98.35% Unkown
HY-125143 ABC34 Inhibitor 99.90% Unkown
HY-RS00495 AIG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18545 Sez6l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22100 Aig1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28620 Aig1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta AIG1 VGNC VGNC:69667
Rattus norvegicus AIG1 RGD RGD:1562920
Canis familiaris AIG1 VGNC VGNC:37740
Felis catus AIG1 VGNC VGNC:59702
Bos taurus AIG1 VGNC VGNC:25764
Mus musculus AIG1 MGD MGI:1913503
Others AIG1 NCBI