TAC1 - tachykinin precursor 1 Gene

Also Known as NK2; NPK; NKNA; TAC2; Hs.2563

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6863

About TAC1

Cytogenetic location: 7q21.3 Genomic coordinates (GRCh38): 7:97,732,086-97,740,472 (from NCBI)

This gene has 5 transcripts (splice variants) and 195 orthologues. Biased expression in brain (RPKM 24.6), spleen (RPKM 12.4) and 6 other tissues.

Summary

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These Hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with Antibacterial and Antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

TAC1 Products (4)

mRNA	Protein	Name
NM_003182.3	NP_003173.1	protachykinin-1 isoform beta precursor
NM_013996.3	NP_054702.1	protachykinin-1 isoform alpha precursor
NM_013997.3	NP_054703.1	protachykinin-1 isoform gamma precursor
NM_013998.3	NP_054704.1	protachykinin-1 isoform delta precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Referencias	Source
enables neuromedin K receptor binding	IPI IPI: Inferred from physical interaction	12716968	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	12609765	GOA
enables receptor ligand activity	IDA IDA: Inferred from direct assay	12716968	GOA
enables substance K receptor binding	IPI IPI: Inferred from physical interaction	12716968	GOA
enables substance P receptor binding	IPI IPI: Inferred from physical interaction	12716968	GOA

Biological Process GO Annotation	Evidence	Referencias	Source
involved in antibacterial humoral response	IDA IDA: Inferred from direct assay	18603306	GOA
involved in antifungal humoral response	IDA IDA: Inferred from direct assay	18603306	GOA
involved in antimicrobial humoral immune response mediated by antimicrobial peptide	IDA IDA: Inferred from direct assay	12074933	GOA
involved in defense response to Gram-negative bacterium	IDA IDA: Inferred from direct assay	18603306	GOA
involved in defense response to Gram-positive bacterium	IDA IDA: Inferred from direct assay	18603306	GOA
involved in detection of temperature stimulus involved in sensory perception of pain	IDA IDA: Inferred from direct assay	17655832	GOA
involved in innate immune response	IDA IDA: Inferred from direct assay	18603306	GOA
involved in killing of cells of another organism	IDA IDA: Inferred from direct assay	12074933	GOA
involved in negative regulation of systemic arterial blood pressure	IDA IDA: Inferred from direct assay	12716968	GOA
involved in positive regulation of cytosolic calcium ion concentration	IDA IDA: Inferred from direct assay	8957234	GOA
involved in positive regulation of flagellated sperm motility	IDA IDA: Inferred from direct assay	17437961	GOA
involved in positive regulation of sensory perception of pain	IDA IDA: Inferred from direct assay	17655832	GOA
involved in regulation of sensory perception of pain	IDA IDA: Inferred from direct assay	17101218	GOA
involved in response to yeast	IDA IDA: Inferred from direct assay	18603306	GOA
involved in tachykinin receptor signaling pathway	IDA IDA: Inferred from direct assay	12716968	GOA

Cellular Component GO Annotation	Evidence	Referencias	Source
located in extracellular space	IDA IDA: Inferred from direct assay	17101218	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
protachykinin-1	PPT

Recombinant TAC1 Proteins

Referencia número	Nombre del producto	Accession	Pureza
HY-P71128	TAC1 Protein, Human (His)	P20366 (E20-R129)	≥ 95%, as determined by reducing SDS-PAGE.

TAC1 Antibodies

Referencia número	Nombre del producto	Aplicación	Reactivity
HY-P81130	Substance P Antibody	IHC-P, IHC-F, ICC/IF, FC, IF-Tissue	Human, Mouse, Rat, Guinea Pig

Related Diseases

Diseases	Alias
Vasomotor Rhinitis	Rhinitis, Vasomotor Rhinitis Vasomotor Vmr - [Vasomotor Rhinitis]
Cystitis	Infective Cystitis Urocystitis Pyocystitis
Bronchitis	Chronic Bronchitis Acute Bronchitis Bronchitis, Chronic Acute Bronchitis And Bronchiolitis Chest Cold Chest Infection Ci - Chest Infection Recurrent Wheezy Bronchitis Bronchitis Chronic Lower Respiratory Tract Infection Acute Lower Respiratory Tract Infection Chronic Bronchitis Nos Senile Bronchitis Bronchitis Nos In Those Under L5 Years Of Age Bronchitis Nos
Cryptosporidiosis	Cryptosporidial Gastroenteritis Intestinal Cryptosporidiosis Infection By Cryptosporidium Gastroenteritis Due To Cryptosporidium Cryptosporidial Infection
Carpal Tunnel Syndrome	Cts Carpal Tunnel Syndrome, Familial Carpal Tunnel Syndrome 1 CTS1 Amyotrophy, Thenar, Of Carpal Origin Carpal Tunnel Median Neuropathy Cts - Carpal Tunnel Syndrome Median Nerve Entrapment Carpal Canal Carpal Tunnel Compression Neuropathy, Carpal Tunnel Distal Median Nerve Compression Distal Median Nerve Entrapment Entrapment Neuropathy, Carpal Tunnel Median Neuropathy, Carpal Tunnel Median Neuropathy Carpal Tunnel Thenar Amyotrophy Of Crapal Origin
Taylor'S Syndrome	Pelvic Congestion Syndrome Congestion-Fibrosis Syndrome Taylor Syndrome
Trigeminal Nerve Disease	Trigeminal Nerve Diseases Disorders Of 5th Cranial Nerve Disorders Of The Fifth Cranial Nerve
Myofascial Pain Syndrome	Myofascial Pain Syndromes Myofascial Pain Dysfunction Syndrome Fibromyalgia
Burning Mouth Syndrome	Orodynia Stomatodynia Stomatopyrosis Bms Burning Mouth Disorder Oral Dysesthesia Sore Mouth Syndrome Bms - [Burning Mouth Syndrome]
Somatoform Disorder	Physiological Malfunction Arising From Mental Factor Psychosomatic Disorder Psychophysiologic Disorders
Hemiplegia	Infantile Hemiplegia Postnatal Infantile Hemiplegia Hemiplegia, Infantile
Constipation
Pain Agnosia	Analgesia
Plantar Fasciitis	Fasciitis, Plantar
Complex Regional Pain Syndrome	Complex Regional Pain Syndromes Reflex Sympathetic Dystrophy Crps
Epicondylitis	Tennis Elbow Lateral Epicondylitis Golfer'S Elbow Medial Epicondylitis Andrel Epicondylitis Archer'S Elbow Hockey Elbow Shooter'S Elbow
Irritable Bowel Syndrome	Irritable Colon Psychogenic Ibs Ibs - [Irritable Bowel Syndrome] Spastic Bowel Syndrome
Glossopharyngeal Neuralgia	Glossopharyngeal Nerve Diseases
Punctate Epithelial Keratoconjunctivitis	Punctate Keratitis Thygeson Superficial Punctate Keratitis Thygeson'S Superficial Punctate Keratitis Thygeson Superficial Punctate Keratopathy Punctate Epithelial Keratitis
Agnosia	Dyspraxia Primary Visual Agnosia Dyspraxia Syndrome Monomodal Visual Amnesia Visual Amnesia Agnosia, Primary Visual Apraxias Alexia
Keratopathy
Interstitial Cystitis	Bladder Pain Syndrome Painful Bladder Syndrome Ulcerative Cystitis Ic/Bps Ic/Pbs Interstitial Cystitis/Bladder Pain Syndrome Interstitial Cystitis/Painful Bladder Syndrome Cystitis, Interstitial Chronic Interstitial Cystitis Pelvic Congestion Syndrome Trigonitis
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Reflex Sympathetic Dystrophy	Algodystrophy Reflex Sympathetic Dystrophy Syndrome Complex Regional Pain Syndrome Type 1 Complex Regional Pain Syndromes Algodystrophic Syndrome
Autonomic Nervous System Disease	Autonomic Nervous System Dysfunction Autonomic Nervous System Disorders Autonomic Nervous System Disorder Autonomic Nervous System Diseases Abnormality Of The Autonomic Nervous System
Meningoencephalitis	Acquired Toxoplasmal Meningoencephalitis Meningoencephalitis Due To Acquired Toxoplasmosis Meningoencephalitis Due To Toxoplasmosis Toxoplasma Meningoencephalitis
Causalgia	Complex Regional Pain Syndrome, Type Ii Complex Regional Pain Syndrome Type 2
Carbamazepine Allergy	Carbamazepen Allergy Tegretol Allergy
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Hyperhidrosis, Gustatory	Frey Syndrome Gustatory Sweating Auriculotemporal Nerve Syndrome Gustatory Hyperhidrosis Frey'S Syndrome Sweating, Gustatory HYPRG Baillarger Syndrome Hyperhidrosis Gustatory Auriculotemporal Syndrome
Aids Phobia
Patellofemoral Pain Syndrome
Allergic Rhinitis	Hay Fever Allergic Rhinitis, Susceptibility To ALRH Atopic Rhinitis Seasonal Allergic Rhinitis Non-Seasonal Allergic Rhinitis Perenial Allergic Rhinitis Pollenosis Rhinitis Allergic Seasonal Rhinitis, Allergic, Perennial Allergic Rhinitis, Cause Unspecified Pollinosis Pollen Allergy Allergy Nos Due To Pollen Summer Catarrh Other Seasonal Allergic Rhinitis
Telogen Effluvium
Motion Sickness	Airsickness Carsickness Seasickness Travel Sickness Riders' Vertigo
Migraine With Or Without Aura 1	Migraine Migraine With Or Without Aura, Susceptibility To, 1 Migraine Disorder Migraine Variant Migraines Migraine Disorders Mgr1 Mgau Ma Migraine With Or Without Aura Classic Migraine Common Migraine Disorder, Migraine Headache Migraine Headache Migrainous Migraine Headache Migraine Syndrome Headache Including Migraine Migraine, Susceptibility To
Detrusor Sphincter Dyssynergia	Detrusor And Sphincter Dyssynergia
Neurogenic Bowel
Diabetic Polyneuropathy	Diabetes Mellitus With Polyneuropathy Polyneuropathy In Diabetes Diabetic Polyneuropathies Diabetic Neuropathy Nos
Recurrent Corneal Erosion	Recurrent Erosion Of Cornea Recurrent Erosion Syndrome Corneal Erosion Non-Traumatic Recurrent Erosion Of Cornea
Aspiration Pneumonia	Pneumonia, Aspiration Pneumonia Aspiration Aspiration Pneumonitis
Urticaria	Nettle Rash Hives Wheal Urticaria Nos
Nerve Compression Syndrome	Entrapment Neuropathies Compression Neuropathy Entrapment Neuropathy Peripheral Nerve Entrapment Syndrome Nerve Compression Syndromes Hereditary Liability To Pressure Palsies
Mononeuropathy	Mononeuropathies
Patellar Tendinitis	Patellar Tendonitis
Sleep Apnea	Sleep Apnea Syndromes
Calcific Tendinitis	Calcific Tendinitis Nos
Paine Syndrome	Pain Disorder Pain Microcephaly With Spastic Diplegia Pain Syndrome
Bladder Neck Obstruction	Obstruction Of Bladder Neck Or Vesicourethral Orifice Urinary Bladder Neck Obstruction Bladder Outlet Obstruction Vesicourethral Orifice Obstruction Bno - [Bladder Neck Obstruction] Bladder Obstruction Nos Acquired Bladder Neck Obstruction Acquired Obstruction Of Bladder Neck Or Vesicourethral Orifice Bladder Neck Strangulation Bladder Neck Stricture Bladder Outflow Obstruction Contracture Of Bladder Neck Or Sphincter Contracture Of Bladder Neck Obstructed Vesicourethral Orifice Strangulation Of Vesicourethral Orifice Stricture Of Vesicourethral Orifice Urinary Prostatic Valve Obstruction Vesical Obstruction
Somatization Disorder	Somatoform Disorders Briquet'S Disorder Polysomatising Disorder Somatisation Disorder Somatoform Disorder
Glossopharyngeal Nerve Disease	Ninth Cranial Nerve Disease Glossopharyngeal Nerve Diseases Disorders Of The Ninth Cranial Nerve Disorders Of 9th Cranial Nerve
Panic Disorder	Panic Anxiety Syndrome Panic Panic Disorder 1 Episodic Paroxysmal Anxiety Disorder
Urethral Syndrome	Urethral Disease Urethral Diseases Urethra Disease Abnormality Of The Urethra Urethral Disorders
Hypertrophic Pyloric Stenosis	Congenital Hypertrophic Pyloric Stenosis Pyloric Stenosis, Hypertrophic Congenital Or Infantile Stricture Of Pylorus Achalasia Of The Pylorus Congenital Hypertrophy Of The Pylorus Infantile Hypertrophy Of The Pylorus Infantile Constriction Of The Pylorus Congenital Stenosis Of The Pylorus Congenital Constriction Of The Pylorus Congenital Stricture Of The Pylorus Infantile Hypertrophic Pyloric Stenosis Infantile Stenosis Of The Pylorus Infantile Stricture Of The Pylorus Congenital Or Infantile Constriction Of Pylorus Infantile Pyloric Obstruction Infantile Pyloric Hypertrophy Pylorus Achalasia Pyloric Constriction Infantile Pyloric Stricture Infantile Pyloric Stenosis Congenital Spasm Of Pylorus Congenital Pylorospasm Congenital Pyloric Stricture Congenital Pyloric Spasm Congenital Or Infantile Spasm Of Pylorus Congenital Or Infantile Obstruction Of Pylorus Congenital Pyloric Stenosis
Ocular Hyperemia	Hyperemia Eye Hyperemia Of Conjunctiva
Neurodermatitis
Nosophobia
Bursitis	Bursitis, Not Otherwise Specified Inflammation Of Bursa
Trigeminal Neuralgia	Tic Douloureux Trifacial Neuralgia Trifocal Neuralgia Neuralgia Of The Fifth Cranial Nerve Neuralgia Of 5th Cranial Nerve Infraorbital Neuralgia
Cough Variant Asthma
Impotence	Erectile Dysfunction Sexual Impotence Erectile Dysfunction Adverse Event
Tendinitis	Tendinopathy
Lateral Medullary Syndrome	Posterior Inferior Cerebellar Artery Syndrome Wallenberg Syndrome Vertebral Artery Syndrome Wallenberg'S Syndrome Pica Syndrome
Shoulder Impingement Syndrome	Impingement Syndrome Of Shoulder Region Subacromial Impingement
Arachnoiditis	Spinal Arachnoiditis Adhesive Arachnoiditis Chronic Arachnoiditis Familial Spinal Arachnoiditis Arachnitis Arachnoid Inflammation
Dermatographia	Dermatographic Urticaria Dermographism Symptomatic Dermographism Urticaria Factitia Factitious Urticaria Dermatographism
Periarthritis
Anismus
Chronic Cystitis
Diarrhea	Diarrhoea Diarrhea Of Presumed Infectious Origin
Plica Syndrome	Synovitis
Sudden Infant Death Syndrome	SIDS Sudden Infant Death Syndrome, Susceptibility To Cot Death Crib Death Sudden Death Of Nonspecific Cause In Infancy Sudden Infant Death Death, Sudden, Syndrome, Infant
Lagophthalmos	Defective Lid Closure Poor Closure Eyelids
Speech And Communication Disorders	Language Disorder Communication Disorder Language Disorders Communication Disorders Speech Language Disorder Speech-Language Disorder Communication Impairment Speech And Language Disorder
Anxiety	Anxiety Disorder Anxiety Disorders Anxiety State Anxieties Anxiety Neurosis
Chronic Rhinitis	Rhinitis - Chronic Chronic Rhinitis Nos Rhinitis Rhinitis Nos
Cancerophobia	Cancer Phobia Fear Of Getting Cancer
Specific Developmental Disorder
Paralytic Ileus	Adynamic Ileus Paralytic Ileus Of Bowel Ileus Nos Paralysis Of Bowel Paralysis Of Intestine Adynamic Intestinal Obstruction Paralytic Intestinal Ileus
Allergic Disease	Hypersensitivity Allergic Hypersensitivity Disease Allergic Condition Allergic Reaction Allergic Disposition
Corneal Ulcer	Cornea Ulcer Ulcerative Keratitis Corneal Ulcer Nos
Functional Gastric Disease
Neurogenic Bladder	Neurogenic Dysfunction Of The Urinary Bladder Neurogenic Urinary Bladder Disorder Neuropathic Bladder Bladder Neurogenic Urinary Bladder, Neurogenic Neurogenic Urinary Bladder
Radiculopathy	Pinched Nerve Nerve Root Disorder Radiculopathy, Site Unspecified Radicular Neuropathy Radicular Syndrome Radicular Pain Radiculitis Radiculitis Nos Spinal Root Pain Nerve Root Neuritis Radiculopathy In Spondylosis
Spondylosis	Lumbar Spondylosis With Myelopathy Lumbosacral Spondylosis Without Myelopathy Spondylogenic Compression Of Lumbar Spinal Cord Spondylogenic Compression Of Thoracic Spinal Cord Spondylosis With Myelopathy Thoracic Or Lumbar Spondylosis With Myelopathy
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Diabetic Neuropathy	Diabetic Neuropathies
Diabetic Autonomic Neuropathy	Diabetic Neuropathies
Nasal Cavity Disease	Disorder Of Nasal Cavity
Frozen Shoulder	Adhesive Capsulitis Of Shoulder Bursitis Adhesions-Capsulitis,Shoulder Pericapsulitis Of Shoulder Duplay Bursitis Adhesive Shoulder Peritendinitis Subscapular Adhesion Shoulder Adhesion Adhesive Enthesopathy Of Shoulder Region Adhesive Peritendinitis Adhesive Shoulder Tenosynovitis Duplay Periarthritis Adhesive Shoulder Tendinitis
Physical Urticaria	Symptomatic Dermographism
Blepharospasm
Brain Stem Infarction	Brain Stem Infarctions Brainstem Infarction
Focal Dystonia	Dystonia, Focal, Task-Specific
Irritant Dermatitis	Irritant Contact Dermatitis Primary Irritant Dermatitis Dermatitis, Irritant Contact Dermatitis, Irritant Irritant Contact Eczema Icd - [Irritant Contact Dermatitis] Irritant Contact Dermatitis, Unspecified Cause Non-Allergic Contact Dermatitis Irritant Contact Eczema Due To Wet Work Irritant Contact Dermatitis Due To Detergents Irritant Contact Eczema Due To Solvents Irritant Contact Eczema Due To Exposure To Acids, Alkalis Or Other Chemical Irritants Irritant Contact Eczema Due To Cosmetics Or Emollients Irritant Contact Eczema Due To Topical Medicaments Or Antimicrobials Irritant Contact Eczema Due To Plants Or Other Vegetable Matter Irritant Contact Eczema Due To Foods Irritant Contact Eczema Due To Friction, Sweating Or Contact With Body Fluids Irritant Contact Eczema Due To Saliva Irritant Contact Eczema Due To Incontinence Incontinence-Associated Dermatitis
Nose Disease	Nose Diseases Disorder Of The Nose Nasal Disorder Abnormality Of The Nose
Alternating Hemiplegia Of Childhood	Alternating Hemiplegia Ahc Alternating Hemiplegia Syndrome Hemiplegia, Alternating, Of Childhood Hemiplegia, Crossed
Photokeratitis
Spondylolisthesis	Slipped Vertebrae Acquired Spondylolisthesis
Dental Pulp Disease	Dental Pulp Diseases Dental Pulp Disorder Disorder Of Pulp Of Tooth Pulp Disorder
Spastic Entropion
Pulmonary Disease, Chronic Obstructive	Chronic Obstructive Pulmonary Disease COPD Pulmonary Disease, Chronic Obstructive, Severe Early-Onset Chronic Obstructive Lung Disease Chronic Obstructive Airway Disease Pulmonary Disease, Chronic Obstructive, Susceptibility To Cold Severe Early-Onset Chronic Obstructive Pulmonary Disease Pulmonary Disease Chronic Obstructive Pulmonary Disease, Obstructive, Chronic, Susceptibility To Chronic Obstructive Pulmonary Disease Of Horses Common Cold Upper Respiratory Infections Copd - [Chronic Obstructive Pulmonary Disease] Coad - [Chronic Obstructive Airways Disease] Cold - [Chronic Obstructive Lung Disease] Chronic Airway Disease Nos Chronic Airways Limitation, Unspecified Chronic Obstructed Airway, Unspecified Chronic Obstructive Airway Disease, Unspecified Chronic Obstructive Airway, Unspecified Obstructive Lung Disease Nos Chronic Obstructive Lung Disease Nos Chronic Obstructive Lung Nos Obstructive Pulmonary Disease Nos Exacerbation Copd Nos Acute Exacerbation Copd
Opioid Abuse	Opioid-Related Disorders
Bruxism	Sleep Bruxism Sleep-Related Bruxism Bruxism - Teeth Grinding Grinding Teeth Sleep Related Bruxism Teeth Grinding Sleep Related Teeth Grinding
Dry Eye Syndrome	Dry Eye Syndromes Dry Eye Disease Tear Film Insufficiency Xerophthalmia
Contact Dermatitis	Contact Dermatitis/Eczema Contact Eczema Dermatitis Venenata Dermatitis, Venenata Dermatitis Contact Dermatitis, Contact
Lacrimal Apparatus Disease	Lacrimal Apparatus Diseases
Serotonin Syndrome	Serotonergic Syndrome Serotonin Storm Serotonin Toxicity Serotonin Toxidrome Malignant Carcinoid Syndrome
Acute Salpingo-Oophoritis	Acute Salpingitis And Oophoritis
Sensory Peripheral Neuropathy	Sensory Neuropathy Peripheral Sensory Neuropathy Hereditary Sensory And Autonomic Neuropathies
Taeniasis	Beef Tapeworm Infection Infection By Taeniarhynchus Saginatus Taenia Saginata Infectious Disease Taenia Saginata Infection Pork Tapeworm Infection Armed Tapeworm Infection Infection By Taenia Solium Intestinal Taenia Solium Infection Pork Tapeworm Taenia Solium Taeniasis Adult Pork Tapeworm Infection Adult Pork Tapeworm Beef Tapeworm Infection By Taenia Saginata Unarmed Tapeworm Infection Taenia Saginata Taeniasis Infection Due To Adult Tapeworm Taenia Saginata Mediocanellata Taenia Infection Infestation By Taenia Saginata Infestation By Taenia Mediocanellata
Sigmoid Disease	Sigmoid Diseases
Perianal Hematoma	External Thrombosed Haemorrhoids Thrombosed External Hemorrhoids
Corneal Disease	Corneal Diseases Corneal Disorders
Migraine With Aura	Classic Migraine Migraine With Typical Aura Migraine Accompagnée Complicated Migraine Classical Migraine Acute Migraine With Aura
Erythromelalgia	Primary Erythromelalgia Erythermalgia Primary Erythermalgia Mitchell Disease Familial Erythromelalgia
Congenital Central Hypoventilation Syndrome	Cchs Haddad Syndrome Ondine Curse Ondine Syndrome Congenital Central Hypoventilation Congenital Central Alveolar Hypoventilation Syndrome Congenital Failure Of Autonomic Control Ondine'S Curse Primary Alveolar Hypoventilation Ondine-Hirschsprung Disease Central Congenital Hypoventilation Syndrome Congenital Ondine Curse Idiopathic Congenital Central Alveolar Hypoventilation Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome Ondine-Hirschsprung Syndrome
Femoral Cancer	Femoral Neoplasms Cancer Of The Femur Femoral Neoplasm Neoplasm Of Femur
Bladder Tuberculosis	Tuberculous Cystitis Tuberculosis Of Bladder
Sleep Disorder	Sleep Disorders Non-Organic Sleep Disorder
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Interval Angle-Closure Glaucoma	Intermittent Angle-Closure Glaucoma Angle-Closure Glaucoma, Subacute Prodromal Angle Closure Glaucoma
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Respiratory Failure	Acute Respiratory Failure Chronic Respiratory Failure Respiratory Insufficiency Acute-On-Chronic Respiratory Failure Respiratory Disease Acute And Chronic Respiratory Failure Respiratory Insufficiency/Failure Chronic Respiratory Disease Pulmonary Valve Insufficiency Chronic Disease Of Respiratory System Respiration Disorders Respiratory Tract Diseases Lung Failure Nos Pulmonary Failure Arf - [Acute Respiratory Failure] Acute Respiratory Insufficiency Acute Pulmonary Insufficiency Acute Respiration Failure Chronic Respiration Failure
Sarcoidosis 1	Sarcoidosis Boeck Sarcoid Besnier-Boeck-Schaumann Disease SS1 Sarcoidosis, Susceptibility To, 1 Lymphogranulomatosis Hodgkin Disease Boeck'S Disease Boeck'S Sarcoid Schaumann'S Disease Or Syndrome Hutchinson-Boeck Disease Or Syndrome
Disease Of Mental Health	Mental Health Mental Disorders
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Transient Refractive Change
Epidermolysis Bullosa Simplex Localized Type	Epidermolysis Bullosa Simplex, Weber-Cockayne Type Weber-Cockayne Syndrome Ebs-Loc Epidermolysis Bullosa Simplex Of Palms And Soles Epidermolysis Bullosa Simplex Weber-Cockayne Type Epidermolysis Bullosa Simplex, Localized Epidermolysis Bullosa Of Hands And Feet Weber-Cockayne Type Epidermolysis Bullosa Simplex Localized Epidermolysis Bullosa Simplex Localized Ebs
Acute Anterolateral Myocardial Infarction	Acute Myocardial Infarction Of Anterolateral Wall
Akinetopsia
Breast Juvenile Papillomatosis	Juvenile Papillomatosis Of The Breast
Hirschsprung Disease 1	Hirschsprung Disease Aganglionic Megacolon Hscr Hirschsprung'S Disease Congenital Megacolon Congenital Intestinal Aganglionosis Colonic Aganglionosis Hirschsprung Disease, Susceptibility To, 1 Hirschsprung Disease, Protection Against HSCR1 Mgc Pelvirectal Achalasia Total Intestinal Aganglionosis Megacolon, Aganglionic Macrocolon Hscr 1 Hirschsprung Disease Type 1 Hirschsprung Disease, Type 1 Congenital Dilatation Of Colon Aganglionosis Congenital Aganglionic Megacolon Aganglionosis Of Colon Bowel Aganglionosis Colon Aganglionosis Hirschsprung Megacolon
Choreatic Disease	Chorea Hereditary Chorea
Endobronchial Lipoma
Dermatitis, Atopic	Atopic Dermatitis Atopic Eczema Dermatitis, Atopic, Susceptibility To, 1 Atod Eczema, Atopic Dermatitis, Atopic 1 Allergic Dermatitis Atopic Neurodermatitis Besnier'S Prurigo Dermatitis, Atopic, 1 Dermatitis Atopic Eczema Besnier Prurigo
Diabetes Mellitus	Diabetes
Parkinson Disease, Late-Onset	Parkinson Disease Parkinson'S Disease PD PARK Parkinson Disease, Susceptibility To Late Onset Parkinson'S Disease Late Onset Parkinson Disease Paralysis Agitans Primary Parkinsonism Idiopathic Parkinson Disease Parkinson'S Parkinson Disease, Late-Onset, Susceptibility To Parkinson Disease, Age Of Onset, Modifier Lewy Body Parkinson Disease Idiopathic Parkinson'S Disease Pd - [Parkinson Disease] Parkinson Disease Nos Parkinson, Nos Primary Parkinson Disease
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-RS14136	TAC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18639	Tac1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25124	Tac1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TAC1	VGNC	VGNC:78078
Felis catus	TAC1	VGNC	VGNC:65915
Bos taurus	TAC1	VGNC	VGNC:35555
Canis familiaris	TAC1	VGNC	VGNC:47061
Mus musculus	TAC1	MGD	MGI:98474
Rattus norvegicus	TAC1	RGD	RGD:3807
Others	TAC1	NCBI