P-8977
P-8977 is a potent dual CO/5-LO inhibitor (IC50 = 0.01 µM). P-8977 can also inhibit cyclooxygenase (CO) (IC50 = 0.53 µM) in 3T3 cells. P-8977 can inhibit ear edema. P-8977 can be used for research on inflammatory skin conditions.
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- No. CAS: 135810-00-3
- Fòrmula: C18H17NO4
- Peso molecular:311.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
0.01 μM
Compound: 24h
|
Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant
Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant
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[PMID: 8568814] |
Chemical Information
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No. CAS 135810-00-3
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Peso molecular 311.33
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Fòrmula C18H17NO4
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SMILES
O=C1C2=C(COC3=CC=C(CCC(N(C)O)=O)C=C13)C=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
P-8977 Related Classifications
HY-108109 Related Classifications
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