APC - APC regulator of WNT signaling pathway Gene

Also Known as APC1

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100517932

About APC

Primary_assembly 2: 116,812,582-117,034,887 reverse strand.Sscrofa11.1:CM000813.5

This gene has 3 transcripts (splice variants), 169 orthologues and 1 paralogue. Ubiquitous expression in mixtures (RPKM 1.1), lung (RPKM 8.9) and 8 other tissues.

APC Products (1)

mRNA Protein Name
NM_001206430.1 NP_001193359.1 adenomatous polyposis coli protein

APC Protein Structure

APC_N_CC

APC_N_CC: pfam16689 (3 - 54)

Smc

Smc: cl34174 (13 - 261)

Suppressor_APC

Suppressor_APC: pfam11414 (132 - 206)

ARM

ARM: smart00185 (339 - 391)

APC_rep

APC_rep: pfam18797 (392 - 465)

ARM

ARM: sd00043 (464 - 507)

ARM

ARM: smart00185 (511 - 552)

ARM

ARM: sd00043 (515 - 552)

ARM

ARM: sd00043 (562 - 594)

ARM

ARM: sd00043 (602 - 643)

ARM

ARM: smart00185 (648 - 688)

ARM

ARM: sd00043 (652 - 686)

Arm

Arm: pfam00514 (690 - 730)

ARM

ARM: sd00043 (694 - 730)

Arm_APC_u3

Arm_APC_u3: pfam16629 (731 - 1018)

APC_u5

APC_u5: pfam16630 (1035 - 1134)

APC_r

APC_r: pfam05923 (1258 - 1275)

APC_u9

APC_u9: pfam16633 (1284 - 1369)

APC_r

APC_r: pfam05923 (1372 - 1394)

APC_r

APC_r: pfam05923 (1639 - 1662)

APC_u13

APC_u13: cl25008 (1664 - 1717)

SAMP

SAMP: pfam05924 (1721 - 1739)

APC_u14

APC_u14: pfam16635 (1748 - 1841)

APC_u15

APC_u15: pfam16636 (1875 - 1949)

SAMP

SAMP: pfam05924 (2036 - 2055)

APC_basic

APC_basic: pfam05956 (2226 - 2571)

EB1_binding

EB1_binding: pfam05937 (2673 - 2846)

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  • 2000
  • 2500
  • 2847 a.a.
Protein Preferred Names Protein Names

adenomatous polyposis coli protein

  • APC, WNT signaling pathway regulator

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112968 Human protein C / Unkown

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124955 proTAME Inhibitor 98.20% Unkown
HY-110287 Apcin Inhibitor 99.62% Unkown
HY-13255 TAME Inhibitor 99.51% Unkown
HY-130841 Apcin-A Inhibitor 98.0% Unkown
HY-P1918 Activated Protein C (390-404), human 98.74% Unkown
HY-13255A TAME hydrochloride Inhibitor 98.31% Unkown
HY-122142A Pyr-​Pro-​Arg-​pNA (hydrochloride) Substrate 99.24% Unkown
HY-182052 Ferroptosis inducer-16 Inhibitor / Unkown
HY-112968A Bovine Protein C / Unkown
HY-122142 Pyr-​Pro-​Arg-​pNA Substrate / Unkown
HY-126016 MAI-400 Inhibitor / Unkown
HY-P1918A Activated Protein C (390-404), human TFA / Unkown
HY-116473 CFM-1 Antagonist / Unkown
HY-179012 CDC20/HSP90-IN-1 Inhibitor / Unkown
HY-172401 CDC20-IN-2 Inhibitor / Unkown
HY-W614725 Apcin-A monohydrochloride Inhibitor / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992193 Anti-B7-H7 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens APC NCBI NCBI:324
Macaca fascicularis APC NCBI NCBI:102126553
Mus musculus APC NCBI NCBI:11789
Susscrofa domestica APC NCBI
Rattus norvegicus APC NCBI NCBI:24205