DDR1 - discoidin domain receptor tyrosine kinase 1 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 100856512

About DDR1

Primary_assembly 12: 798,388-816,365 forward strand.ROS_Cfam_1.0:CM025111.1

This gene has 5 transcripts (splice variants), 196 orthologues and 54 paralogues.

DDR1 Products (8)

mRNA Protein Name
XM_038682941.1 XP_038538869.1 epithelial discoidin domain-containing receptor 1 isoform X1
XM_038682942.1 XP_038538870.1 epithelial discoidin domain-containing receptor 1 isoform X2
XM_038682944.1 XP_038538872.1 epithelial discoidin domain-containing receptor 1 isoform X4
XM_038682948.1 XP_038538876.1 epithelial discoidin domain-containing receptor 1 isoform X5
XM_038682945.1 XP_038538873.1 epithelial discoidin domain-containing receptor 1 isoform X5
XM_038682947.1 XP_038538875.1 epithelial discoidin domain-containing receptor 1 isoform X5
XM_038682943.1 XP_038538871.1 epithelial discoidin domain-containing receptor 1 isoform X3
XM_038682946.1 XP_038538874.1 epithelial discoidin domain-containing receptor 1 isoform X5

DDR1 Protein Structure

FA58C

FA58C: cd00057 (100 - 251)

PTKc_DDR1

PTKc_DDR1: cd05096 (674 - 977)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 984 a.a.
Protein Preferred Names Protein Names

LOW QUALITY PROTEIN: epithelial discoidin domain-containing receptor 1

epithelial discoidin domain-containing receptor 1

  • discoidin domain receptor family, member 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-16961 Sitravatinib Inhibitor 99.57% Phase 3
HY-16961A Sitravatinib malate Inhibitor / Phase 3
HY-157442 GLPG3312 Inhibitor 98.63% Phase 1

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135401 VU6015929 Inhibitor 99.50% Unkown
HY-114173 DDR1-IN-4 Inhibitor 98.19% Unkown
HY-NP175 Collagen (bovine skin) Ligand / Unkown
HY-133670 DDR1-IN-6 Inhibitor 98.02% Unkown
HY-156552 DDR1/2 inhibitor-2 Inhibitor 99.73% Unkown
HY-13979A DDR1-IN-1 dihydrochloride Inhibitor 98.92% Unkown
HY-133669 DDR1-IN-5 Inhibitor 99.65% Unkown
HY-176184 PROTAC DDR1 degrader-1 Degrader 98.69% Unkown
HY-167208 SR-302 Inhibitor 98.51% Unkown
HY-183068 AP4-43 Inhibitor / Unkown
HY-176185 DDR1 ligand 1 / Unkown
HY-175281 SJ11646 Degrader / Unkown
HY-179535 Axl-IN-21 Inhibitor / Unkown
HY-173284 DDR1-IN-11 Inhibitor / Unkown
HY-181839 DDR1/2 IN-4 Inhibitor / Unkown
HY-122848 DDR1/2 inhibitor-3 Inhibitor / Unkown
HY-162102 DDR1-IN-8 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DDR1 NCBI NCBI:780