2. Gene
  3. IDH1 - isocitrate dehydrogenase (NADP(+)) 1 Gene

IDH1 - isocitrate dehydrogenase (NADP(+)) 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa

Also known as IDH; IDP

Gene ID: 102166364 | Gene type: protein coding

About IDH1

Primary_assembly 15: 111,341,153-111,362,296 reverse strand.Sscrofa11.1:CM000826.5

This gene has 4 transcripts (splice variants), 233 orthologues and 1 paralogue. Broad expression in subcutaneous adipose (RPKM 72.3), liver (RPKM 67.5) and 7 other tissues.

IDH1 Products(5)

mRNA Protein Name
XM_005672136.3 XP_005672193.1 isocitrate dehydrogenase [NADP] cytoplasmic isoform X2
XM_021074908.1 XP_020930567.1 isocitrate dehydrogenase [NADP] cytoplasmic isoform X1
XM_013984432.2 XP_013839886.1 isocitrate dehydrogenase [NADP] cytoplasmic isoform X2
XM_013984433.2 XP_013839887.1 isocitrate dehydrogenase [NADP] cytoplasmic isoform X2
XM_005672137.3 XP_005672194.1 isocitrate dehydrogenase [NADP] cytoplasmic isoform X2

IDH1 Protein Structure

PTZ00435

PTZ00435: PTZ00435 (38 - 448)

  • 0
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  • 452 a.a.
Protein Preferred Names Protein Names

isocitrate dehydrogenase [NADP] cytoplasmic

Cytosolic NADP-isocitrate dehydrogenase

Isocitrate dehydrogenase [NADP] cytoplasmic

NADP(+)-specific ICDH

Oxalosuccinate decarboxylase

isocitrate dehydrogenase (NADP(+)) 1, cytosolic

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18767 Ivosidenib Inhibitor 99.89% Yes
HY-104042 Vorasidenib Inhibitor 99.76% Yes
Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-114226 Olutasidenib Inhibitor 99.16% Phase 2
HY-104036 IDH-305 Inhibitor 99.15% Phase 2
HY-145594 Safusidenib Inhibitor 99.05% Phase 2
HY-100020 BAY-1436032 Inhibitor 99.79% Phase 1
HY-131312 Crelosidenib Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (20)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18082 AGI-5198 Inhibitor 99.93% Unkown
HY-19540 GSK864 Inhibitor 99.91% Unkown
HY-128661 IDH1 Inhibitor 2 Inhibitor 98.70% Unkown
HY-112056 DIM-C-pPhCO2Me Inhibitor 99.47% Unkown
HY-128888 (R,R)-GSK321 Inhibitor 99.36% Unkown
HY-12475 Mutant IDH1-IN-1 Inhibitor 99.43% Unkown
HY-128888B (S,R)-GSK321 Control 98.62% Unkown
HY-18717 Mutant IDH1-IN-2 Inhibitor 98.50% Unkown
HY-150238 IDH1 Inhibitor 7 Inhibitor 99.46% Unkown
HY-110144 TC-E 5008 Inhibitor / Unkown
HY-123153 GSK990 Control / Unkown
HY-149359 IHMT-IDH1-053 Inhibitor / Unkown
HY-158319 Mutant IDH1/NAMPT-IN-1 Inhibitor / Unkown
HY-121916 ML309 Inhibitor / Unkown
HY-175213 Mutant IDH1-IN-7 Inhibitor / Unkown
HY-175770 mIDH1-IN-2 Inhibitor / Unkown
HY-120765 BRD2879 Inhibitor / Unkown
HY-100476 Mutant IDH1-IN-3 Inhibitor / Unkown
HY-162631 IDH1 Inhibitor 9 Inhibitor / Unkown
HY-131312A Crelosidenib gentisate Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IDH1 NCBI NCBI:3417