FLT3LG - Flt3lg Fms related receptor tyrosine kinase 3 ligand Gene

Also Known as Gm45713

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 103691134

Summary

Predicted to enable identical protein binding activity and receptor tyrosine kinase binding activity. Involved in positive regulation of natural killer cell proliferation. Predicted to be located in cell surface and extracellular space. Predicted to be intrinsic component of external side of plasma membrane. Used to study pancreatic Cancer. Human ortholog(s) of this gene implicated in colon carcinoma; glioblastoma; and high grade glioma. Orthologous to human FLT3LG (fms related receptor tyrosine kinase 3 ligand). [provided by Alliance of Genome Resources, Apr 2022]

FLT3LG Products (1)

mRNA Protein Name
NM_001305939.1 NP_001292868.1 fms-related tyrosine kinase 3 ligand precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of natural killer cell proliferation IDA
IDA: Inferred from direct assay
16528542 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fms-related tyrosine kinase 3 ligand

  • rCG54594-like

Recombinant FLT3LG Proteins

Cat. No. Product Name Accession Purity
HY-P74150 FLT3LG Protein, Rat (sf9, His) NP_001292868 (T28-Q189) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04993 FLT3LG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23578 Flt3lg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991114 Adezkibart Ligand 96% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FLT3LG NCBI NCBI:2323