Dnm3 - dynamin 3 Gene

Also Known as Dyna III; mKIAA0820; C530045C17; 9630020E24Rik; B230343F03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 103967

Summary

Predicted to enable several functions, including G protein-coupled glutamate receptor binding activity; GTPase activity; and nitric-oxide synthase binding activity. Predicted to be a structural constituent of postsynapse. Involved in synaptic vesicle budding from presynaptic endocytic zone membrane. Located in photoreceptor inner segment and presynapse. Is expressed in several structures, including 1st branchial arch; central nervous system; genitourinary system; musculature; and paraxial mesenchyme. Orthologous to human DNM3 (Dynamin 3). [provided by Alliance of Genome Resources, Apr 2022]

Dnm3 Products (2)

mRNA Protein Name
NM_001038619.2 NP_001033708.1 dynamin-3 isoform 1
NM_172646.3 NP_766234.1 dynamin-3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23640057 MGI
Biological Process GO Annotation Evidence References Source
involved in synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
21689597 MGI
involved in synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
21689597 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
23746204 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
21689597 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynamin-3

  • dynamin III

  • t-dynamin

  • testicular dynamin

Dnm3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Dnm3 Q8BZ98 Amph Mus musculus Q7TQF7
Anti Bait CoIP
23640057
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03906 DNM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnm3 NCBI NCBI:26052