CEACAM7 - CEA cell adhesion molecule 7 Gene

Also Known as CGM2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1087

About CEACAM7

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,673,303-41,688,270 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 569 orthologues and 24 paralogues. Restricted expression toward colon (RPKM 448.6).

Summary

This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal Cancer. Additionally, lower expression levels of this gene may be predictive of rectal Cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

CEACAM7 Products (2)

mRNA Protein Name
NM_001291485.2 NP_001278414.1 carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein
NM_006890.5 NP_008821.2 carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
10436421 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CEACAM7 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (42 - 141)

Ig_2

Ig_2: Immunoglobulin domain (147 - 234)

  • 0
  • 100
  • 200
  • 265 a.a.
Protein Preferred Names Protein Names

carcinoembryonic antigen-related cell adhesion molecule 7

  • carcinoembryonic antigen CGM2

Recombinant CEACAM7 Proteins

Cat. No. Product Name Accession Purity
HY-P7825 CEACAM7 Protein, Human (HEK293, His) AAI21133.1 (T36-F142) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Mucinous Cystadenocarcinoma

  • Cystadenocarcinoma, Mucinous

  • Pseudomucinous Cystadenocarcinoma

  • Cystadenocarcinoma Mucinous
Gastrointestinal Carcinoma

  • Gastrointestinal Neoplasms
Adenosquamous Carcinoma

  • Adenosquamous Cell Carcinoma

  • Mixed Adenocarcinoma And Squamous Carcinoma

  • Carcinoma Adenosquamous

  • Carcinoma, Adenosquamous
Cervical Adenocarcinoma

  • Adenocarcinoma Cervix Uteri

  • Adenocarcinoma Of Cervix

  • Adenocarcinoma Of The Uterine Cervix

  • Adenocarcinoma Of The Cervix Uteri
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Goblet Cell Carcinoid

  • Gcc

  • Goblet Cell Adenocarcinoid

  • Goblet Cell Carcinoma

  • Goblet Cell Tumor

  • Mucinous Carcinoid

  • Carcinoid Goblet Cell

  • Carcinoid, Goblet Cell
Rectum Cancer

  • Malignant Neoplasm Of Rectum

  • Rectal Cancer

  • Cancer Of Rectum

  • Carcinoma Of Rectum

  • Carcinoma Of The Rectum

  • Malignant Rectal Tumor

  • Malignant Rectum Tumor

  • Malignant Tumor Of Rectum

  • Rectal Carcinoma

  • Rectal Cancers

  • Cancer, Rectal
Ovarian Cyst

  • Ovarian Cysts
Paget Disease, Extramammary

  • Extramammary Paget Disease

  • Cutaneous Paget'S Disease

  • Extramammary Paget'S Disease

  • Paget Disease Extramammary

  • Cutaneous Paget Disease

  • Paget'S Disease Of Skin

  • Empd

  • Extramammary Pagets Disease
Pleural Tuberculosis

  • Pearly Disease

  • Tuberculosis Of Pleura

  • Tuberculous Pleurisy

  • Tuberculous Pleurisy In Primary Progressive Tuberculosis

  • Tuberculous Pleuritis

  • Pleurisy Tuberculous

  • Tuberculosis, Pleural

  • Serosal Tuberculosis Of Cattle
Colon Adenocarcinoma

  • Adenocarcinoma Of Colon

  • Adenocarcinoma Of The Colon

  • Colonic Adenocarcinoma
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Lung Cancer Susceptibility 3

  • Lung Adenocarcinoma

  • Adenocarcinoma Of Lung

  • LNCR3

  • Adenocarcinoma Of Lung, Susceptibility To

  • Bronchogenic Lung Adenocarcinoma

  • Nonsmall Cell Adenocarcinoma

  • Adenocarcinoma Lung

  • Lung Adenocarcinomas

  • Non-Small Cell Adenocarcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02443 CEACAM7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990852 Anti-CEACAM7 Antibody (P3-7B) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CEACAM7 VGNC VGNC:109596
Others CEACAM7 NCBI