2. Gene
  3. MAN1A2 - mannosidase alpha class 1A member 2 Gene

MAN1A2 - mannosidase alpha class 1A member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MAN1B

Gene ID: 10905 | Gene type: protein coding

About MAN1A2

Cytogenetic location: 1p12 Genomic coordinates (GRCh38): 1:117,367,449-117,528,872 (from NCBI)

This gene has 5 transcripts (splice variants), 226 orthologues and 6 paralogues. Ubiquitous expression in thyroid (RPKM 10.5), placenta (RPKM 7.6) and 25 other tissues.

Summary

Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.[supplied by OMIM, Mar 2008]

MAN1A2 Products(1)

mRNA Protein Name
NM_006699.5 NP_006690.1 mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

MAN1A2 Protein Structure

Glyco_hydro_47

Glyco_hydro_47: Glycosyl hydrolase family 47 (187 - 626)

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  • 641 a.a.
Protein Preferred Names Protein Names

mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

alpha-1,2-mannosidase IB

Recombinant MAN1A2 Proteins

Cat. No. Product Name Accession Purity
HY-P76485 MAN1A2 Protein, Human (HEK293, His) O60476 (P58-R641) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08005 MAN1A2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MAN1A2 RGD RGD:1309767
Canis familiaris MAN1A2 VGNC VGNC:42943
Macaca mulatta MAN1A2 VGNC VGNC:106404
Bos taurus MAN1A2 VGNC VGNC:31162
Mus musculus MAN1A2 MGD MGI:104676
Felis catus MAN1A2 VGNC VGNC:68145
Others MAN1A2 NCBI