C1qbp - complement component 1, q subcomponent binding protein Gene
Also Known as P32; HABP1; gC1qBP; D11Wsu182e
Species: Mus musculus
Summary
Enables mRNA binding activity and mitochondrial ribosome binding activity. Involved in mature ribosome assembly and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; axial musculature; brain ventricular layer; genitourinary system; and orbito-sphenoid. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 33. Orthologous to human C1QBP (complement C1q binding protein). [provided by Alliance of Genome Resources, Apr 2022]
C1qbp Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_007573.2 | NP_031599.2 | complement component 1 Q subcomponent-binding protein, mitochondrial |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables mRNA binding |
IDA
IDA: Inferred from direct assay
|
22904065 | MGI |
| enables mitochondrial ribosome binding |
IDA
IDA: Inferred from direct assay
|
22904065 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
18460468 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cytosolic ribosome assembly |
IMP
IMP: Inferred from mutant phenotype
|
22904065 | MGI |
| involved in positive regulation of mitochondrial translation |
IMP
IMP: Inferred from mutant phenotype
|
22904065 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in mitochondrion |
IDA
IDA: Inferred from direct assay
|
18166172 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
complement component 1 Q subcomponent-binding protein, mitochondrial |
|
Recombinant C1qbp Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P76185 | HABP1/C1QBP Protein, Mouse (His) | Q8R5L1 (L72-Q279) | ≥ 90%, as determined by reducing SDS-PAGE. |