LAYN - layilin Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 143903

About LAYN

Cytogenetic location: 11q23.1 Genomic coordinates (GRCh38): 11:111,540,280-111,561,745 (from NCBI)

This gene has 10 transcripts (splice variants), 257 orthologues and 1 paralogue. Broad expression in ovary (RPKM 7.0), thyroid (RPKM 6.2) and 20 other tissues.

Summary

Enables hyaluronic acid binding activity. Located in focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]

LAYN Products (4)

mRNA Protein Name
NM_001258390.2 NP_001245319.1 layilin isoform 1 precursor
NM_001258391.2 NP_001245320.1 layilin isoform 3
NM_001318799.1 NP_001305728.1 layilin isoform 4
NM_178834.5 NP_849156.1 layilin isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables hyaluronic acid binding IDA
IDA: Inferred from direct assay
11294894 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LAYN Protein Structure

Lectin_C

Lectin_C: Lectin C-type domain (62 - 185)

  • 0
  • 100
  • 200
  • 300
  • 382 a.a.
Protein Preferred Names Protein Names

layilin

Recombinant LAYN Proteins

Cat. No. Product Name Accession Purity
HY-P73839 Layilin/LAYN Protein, Human (HEK293, His) Q6UX15-2/NP_849156.1 (A22-E220) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73840 Layilin/LAYN Protein, Human (HEK293, Fc) Q6UX15-2/NP_849156.1 (A22-E220) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07541 LAYN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17813 Layn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24281 Layn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LAYN VGNC VGNC:74157
Rattus norvegicus LAYN RGD RGD:1564444
Canis familiaris LAYN VGNC VGNC:42601
Bos taurus LAYN VGNC VGNC:30803
Felis catus LAYN VGNC VGNC:63201
Mus musculus LAYN MGD MGI:2685357
Others LAYN NCBI