Rnf43 - ring finger protein 43 Gene

Also Known as 4732452J19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 207742

Summary

Predicted to enable Frizzled binding activity and ubiquitin protein Ligase activity. Involved in negative regulation of Wnt signaling pathway and stem cell proliferation. Predicted to be located in endoplasmic reticulum; nucleus; and plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in alimentary system; genitourinary system; and lung. Orthologous to human RNF43 (Ring Finger Protein 43). [provided by Alliance of Genome Resources, Apr 2022]

Rnf43 Products (2)

mRNA Protein Name
NM_001363437.1 NP_001350366.1 E3 ubiquitin-protein ligase RNF43 isoform 2
NM_172448.4 NP_766036.2 E3 ubiquitin-protein ligase RNF43 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
31073040 MGI
Biological Process GO Annotation Evidence Références Source
involved in negative regulation of Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
22895187 MGI
involved in stem cell proliferation IMP
IMP: Inferred from mutant phenotype
22895187 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF43

  • RING-type E3 ubiquitin transferase RNF43

Recombinant Rnf43 Proteins

Cat. No. Nom du produit Accession Pureté
HY-P78030 RNF43 Protein, Mouse (HEK293, Fc) Q5NCP0-1 (G24-Y197) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P10810 QPH-FR Inhibitor 99.54% Unkown
HY-RS12093 RNF43 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17844 Rnf43 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24312 Rnf43 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P992297 Anti-RNF43 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf43 NCBI NCBI:54894