Neu2 - neuraminidase 2 Gene

Also Known as MBS; MSS; MTS

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23956

Summary

Enables exo-alpha-(2->3)-sialidase activity and exo-alpha-(2->8)-sialidase activity. Involved in ganglioside catabolic process and oligosaccharide catabolic process. Predicted to be located in cytosol. Predicted to be part of catalytic complex. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. Is expressed in brain. Orthologous to human NEU2 (neuraminidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Neu2 Products (4)

mRNA Protein Name
NM_001160163.1 NP_001153635.1 sialidase-2 isoform 1
NM_001160164.1 NP_001153636.1 sialidase-2 isoform 2
NM_001160165.1 NP_001153637.1 sialidase-2 isoform 3
NM_015750.3 NP_056565.1 sialidase-2 isoform 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables exo-alpha-sialidase activity IDA
IDA: Inferred from direct assay
10713120 MGI
Biological Process GO Annotation Evidence References Source
involved in ganglioside catabolic process IDA
IDA: Inferred from direct assay
10713120 MGI
involved in oligosaccharide catabolic process IDA
IDA: Inferred from direct assay
10713120 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialidase-2

  • N-acetyl-alpha-neuraminidase 2

  • brain sialidase

  • cystolic sialidase

  • cytosolic sialidase

  • murine thymic sialidase

  • skeletal muscle sialidase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-125798 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid Inhibitor ≥99.0% Unkown
HY-121605 RL71 Inducer 97.44% Unkown
HY-P1855 HER2/neu (654-662) GP2 98.26% Unkown
HY-E70715 ERBB2 775YVMA776 Recombinant Human Active Protein Kinase / Unkown
HY-P10569 Biotin HER-2 substrate peptide / Unkown
HY-P5742 ELAAWCRWGFLLALLPPGIAG / Unkown
HY-P5742A ELAAWCRWGFLLALLPPGIAG TFA / Unkown
HY-P5745 TYVPANASL / Unkown
HY-P5745A TYVPANASL TFA / Unkown
HY-RS09216 NEU2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-121605S RL71-d6 / Unkown
HY-183402 FLLL12 / Unkown
HY-RS22251 Neu2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28773 Neu2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neu2 NCBI NCBI:4759