Sulf1 - sulfatase 1 Gene

Also Known as MSulf-1; mKIAA1077

Species: Mus musculus

Gene Type: protein coding
Gene ID: 240725

Summary

Enables N-acetylglucosamine-6-sulfatase activity. Involved in several processes, including esophagus smooth muscle contraction; glomerular filtration; and skeletal system development. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; limb; lower urogenital tract; and sensory organ. Orthologous to human SULF1 (sulfatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sulf1 Products (3)

mRNA Protein Name
NM_001198565.2 NP_001185494.1 extracellular sulfatase Sulf-1 precursor
NM_001198566.2 NP_001185495.1 extracellular sulfatase Sulf-1 precursor
NM_172294.2 NP_758498.1 extracellular sulfatase Sulf-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-acetylglucosamine-6-sulfatase activity IMP
IMP: Inferred from mutant phenotype
18687675 MGI
Biological Process GO Annotation Evidence References Source
involved in bone development IGI
IGI: Inferred from genetic interaction
17593974 MGI
involved in cartilage development IMP
IMP: Inferred from mutant phenotype
20479257 MGI
involved in chondrocyte development IMP
IMP: Inferred from mutant phenotype
20479257 MGI
involved in embryonic skeletal system development IGI
IGI: Inferred from genetic interaction
18213582 MGI
involved in esophagus smooth muscle contraction IGI
IGI: Inferred from genetic interaction
17720696 MGI
involved in glial cell-derived neurotrophic factor receptor signaling pathway IDA
IDA: Inferred from direct assay
17720696 MGI
involved in glomerular basement membrane development IGI
IGI: Inferred from genetic interaction
21719793 MGI
involved in glomerular filtration IGI
IGI: Inferred from genetic interaction
21719793 MGI
involved in heparan sulfate proteoglycan metabolic process IMP
IMP: Inferred from mutant phenotype
18687675 MGI
involved in innervation IGI
IGI: Inferred from genetic interaction
17720696 MGI
involved in kidney development IGI
IGI: Inferred from genetic interaction
17593974 MGI
involved in negative regulation of fibroblast growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
20410206 MGI
involved in negative regulation of fibroblast growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
17593974 MGI
involved in negative regulation of prostatic bud formation IDA
IDA: Inferred from direct assay
20410206 MGI
involved in positive regulation of vascular endothelial growth factor production IGI
IGI: Inferred from genetic interaction
21719793 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
21719793 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

extracellular sulfatase Sulf-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14011 SULF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19746 Sulf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26243 Sulf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sulf1 NCBI NCBI:23213