Cstb - cystatin B Gene

Also Known as Cyb; Epm1; Stfb

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25308

Summary

Predicted to enable cysteine-type endopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of peptidase activity. Predicted to act upstream of or within adult locomotory behavior. Predicted to be located in cytoplasm; extracellular space; and nucleolus. Predicted to be active in cytosol. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in Unverricht-Lundborg syndrome and progressive myoclonus epilepsy 1A. Orthologous to human CSTB (Cystatin B). [provided by Alliance of Genome Resources, Apr 2022]

Cstb Products (1)

mRNA Protein Name
NM_012838.2 NP_036970.1 cystatin-B

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
1239805 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cystatin-B

  • cystatin B (stefin B)

  • cystatin beta

  • liver thiol proteinase inhibitor

  • stefin-B

Cstb Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Cstb P01041 SOD1 Homo sapiens P00441
Anti Bait CoIP
24234043
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03272 CSTB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18470 Cstb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24951 Cstb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cstb NCBI NCBI:1476