Scgb1a1 - secretoglobin family 1A member 1 Gene

Also Known as Ugb; CC10; CC16; CCSP; PCBB

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25575

Summary

Enables polychlorinated biphenyl binding activity. Involved in several processes, including response to lipopolysaccharide; response to ozone; and response to silicon dioxide. Located in several cellular components, including nuclear envelope; rough endoplasmic reticulum; and secretory granule. Biomarker of acute kidney failure; asthma; otitis media; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; asthma; and glomerulonephritis. Orthologous to human SCGB1A1 (secretoglobin family 1A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Scgb1a1 Products (1)

mRNA Protein Name
NM_013051.1 NP_037183.1 uteroglobin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables polychlorinated biphenyl binding IPI
IPI: Inferred from physical interaction
7583672 RGD
Biological Process GO Annotation Evidence References Source
involved in response to cytokine IMP
IMP: Inferred from mutant phenotype
12060562 RGD
involved in response to fibroblast growth factor IEP
IEP: Inferred from expression pattern
11076805 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
9505268 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
18420837 RGD
involved in response to ozone IEP
IEP: Inferred from expression pattern
9028799 RGD
involved in response to silicon dioxide IEP
IEP: Inferred from expression pattern
16369113 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
8117444 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
21787397 RGD
located in nuclear envelope IDA
IDA: Inferred from direct assay
8117444 RGD
located in secretory granule IDA
IDA: Inferred from direct assay
8117444 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uteroglobin

  • CCPBP

  • PCB-binding protein

  • Uteroglobin (club cell secretory protein)

  • club cell 10 kDa secretory protein

  • club cell phospholipid-binding protein

  • club cell protein 16

  • club cells 10 kDa secretory protein

  • club secretory protein-16

  • secretoglobin, family

Recombinant Scgb1a1 Proteins

Cat. No. Product Name Accession Purity
HY-P71925A SCGB1A1 Protein, Rat (His) P17559 (S20-V96) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12504 SCGB1A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18577 Scgb1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25061 Scgb1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scgb1a1 NCBI NCBI:7356