NPTN - neuroplastin Gene

Homo sapiens

Also known as GP55; GP65; SDR1; np55; np65; SDFR1

Gene ID: 27020 | Gene type: protein coding

About NPTN

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:73,560,014-73,633,389 (from NCBI)

This gene has 10 transcripts (splice variants), 311 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 67.5), endometrium (RPKM 61.9) and 25 other tissues.

Summary

This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]

NPTN Products(4)

mRNA	Protein	Name
NM_001161363.2	NP_001154835.1	neuroplastin isoform c precursor
NM_001161364.2	NP_001154836.1	neuroplastin isoform d precursor
NM_012428.4	NP_036560.1	neuroplastin isoform b precursor
NM_017455.4	NP_059429.1	neuroplastin isoform a precursor

NPTN Protein Structure

I-set

Ig_2

I-set

0
100
200
300
398 a.a.

Protein Preferred Names

Protein Names

neuroplastin

SDR-1

Recombinant NPTN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71153	Neuroplastin Protein, Human (192a.a, HEK293, His)	Q9Y639 (Q29-H220)	≥95%
HY-P76521	Neuroplastin Protein, Human (221a.a, HEK293, His)	Q9Y639 (M1-L221)	≥95%

Related Diseases

Diseases

Alias

Erythroleukemia

Retrograde Amnesia

Amnesia, Retrograde

Allergic Bronchopulmonary Aspergillosis

Aspergillosis, Allergic Bronchopulmonary	Abpa
Allergic Bronchopulmonary Mycosis	Hinson-Pepys Disease
Pulmonary Aspergillus Disease	Allergic Aspergillosis
Aspergillosis Allergic Bronchopulmonary

Acute Erythroid Leukemia

Acute Erythroleukemia	Di Guglielmo'S Syndrome
Aml M6	Acute Myeloid Leukemia Fab-M6
Acute Myeloid Leukemia M6	Erythroleukemia
Aml-M6	Acute Erythroleukemia M6a Subtype
Acute Erythroleukemia M6b Subtype	Di Guglielmo Syndrome
Acute Myeloid Leukemia, M6 Type	Acute Erythroblastic Leukemia
Acute Erythroleukemia - M6a Subtype	Acute Erythroleukemia - M6b Subtype
Acute Erythraemia And Erythroleukaemia	Acute Erythroid Leukaemia Without Mention Of Remission
Erythraemia	Erythraemic Myelosis
Erythroleukaemia	Acute Erythraemic Myelosis
Acute Erythraemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09504	NPTN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	NPTN	RGD	RGD:620296
Macaca mulatta	NPTN	VGNC	VGNC:75202
Canis familiaris	NPTN	VGNC	VGNC:43932
Mus musculus	NPTN	MGD	MGI:108077
Felis catus	NPTN	VGNC	VGNC:63876
Bos taurus	NPTN	VGNC	VGNC:32217
Others	NPTN	NCBI