Spib - Spi-B transcription factor (Spi-1/PU.1 related) Gene

Also Known as Spi-B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 272382

Summary

Enables DNA-binding transcription factor activity. Involved in immature B cell differentiation. Acts upstream of or within macrophage differentiation and regulation of transcription, DNA-templated. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in brain and liver. Orthologous to human SPIB (Spi-B transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Spib Products (1)

mRNA Protein Name
NM_019866.1 NP_063919.1 transcription factor Spi-B

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
11980719 MGI
Biological Process GO Annotation Evidence References Source
involved in immature B cell differentiation IGI
IGI: Inferred from genetic interaction
28062693 MGI
acts upstream of or within macrophage differentiation IDA
IDA: Inferred from direct assay
11980719 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11980719 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Spi-B

  • Ets transcription factor Spi-B

  • Spi-1/PU.1 related

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13672 SPIB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22331 Spib Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28853 Spib Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spib NCBI NCBI:6689