MOCS3 - molybdenum cofactor synthesis 3 Gene

Homo sapiens

Also known as UBA4

Gene ID: 27304 | Gene type: protein coding

About MOCS3

Cytogenetic location: 20q13.13 Genomic coordinates (GRCh38): 20:50,958,818-50,963,929 (from NCBI)

This gene has 1 transcript (splice variant), 195 orthologues and 9 paralogues.

Summary

Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. The protein encoded by this gene adenylates and activates molybdopterin synthase, an Enzyme required for biosynthesis of MoCo. This gene contains no introns. A pseudogene of this gene is present on chromosome 14. [provided by RefSeq, Nov 2012]

MOCS3 Products(1)

mRNA	Protein	Name
NM_014484.5	NP_055299.1	adenylyltransferase and sulfurtransferase MOCS3

MOCS3 Protein Structure

ThiF

Rhodanese

0
100
200
300
400
460 a.a.

Protein Preferred Names

Protein Names

adenylyltransferase and sulfurtransferase MOCS3

MPT synthase sulfurylase

Related Diseases

Diseases

Alias

Molybdenum Cofactor Deficiency

Combined Molybdoflavoprotein Enzyme Deficiency	Mocod
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase, And Aldehyde Oxidase	Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase
Combined Xanthine Oxidase And Sulfite Oxidase And Aldehyde Oxidase Deficiency	Deficiency Of Molybdenum Cofactor
Deficiency, Molybdenum Cofactor

Molybdenum Cofactor Deficiency, Complementation Group C

MOCODC	Sulfite Oxidase Deficiency Due To Molybdenum Cofactor Deficiency Type C
Molybdenum Cofactor Deficiency C	Molybdenum Cofactor Deficiency Type C
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase Type C	Mocod Type C
Molybdenum Cofactor Deficiency Complementation Group C	Deficiency, Molybdenum Cofactor, Complementation Group C

Sulfite Oxidase Deficiency, Isolated

Sulfite Oxidase Deficiency	Sulfocysteinuria
Isolated Sulfite Oxidase Deficiency	ISOD
Encephalopathy Due To Sulfite Oxidase Deficiency

Molybdenum Cofactor Deficiency, Complementation Group A

MOCODA	Sulfite Oxidase Deficiency Due To Molybdenum Cofactor Deficiency Type A
Molybdenum Cofactor Deficiency A	Molybdenum Cofactor Deficiency Type A
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase Type A	Mocod Type A
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase, And Aldehyde Oxidase	Sulfite Oxidase, Xanthine Dehydrogenase, And Aldehyde Oxidase, Combined Deficiency Of
Molybdenum Cofactor Deficiency Complementation Group A	Molybdenum Cofactor Deficiency, Type A
Deficiency, Molybdenum Cofactor, Complementation Group A

Molybdenum Cofactor Deficiency, Complementation Group B

MOCODB	Sulfite Oxidase Deficiency Due To Molybdenum Cofactor Deficiency Type B
Molybdenum Cofactor Deficiency B	Molybdenum Cofactor Deficiency Type B
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase Type B	Mocod Type B
Molybdenum Cofactor Deficiency Complementation Group B	Deficiency, Molybdenum Cofactor, Complementation Group B

Neu-Laxova Syndrome 2

NLS2

Encephalomalacia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08582	MOCS3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MOCS3	VGNC	VGNC:43307
Bos taurus	MOCS3	VGNC	VGNC:31549
Macaca mulatta	MOCS3	VGNC	VGNC:74772
Rattus norvegicus	MOCS3	RGD	RGD:1307044
Mus musculus	MOCS3	MGD	MGI:1916622
Felis catus	MOCS3	VGNC	VGNC:63550

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