Wfikkn2 - WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 Gene

Also Known as Gasp1; WFIKKNRP; 2610304F08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 278507

Summary

Predicted to enable receptor antagonist activity and transforming growth factor beta binding activity. Acts upstream of or within several processes, including negative regulation of DNA binding activity; roof of mouth development; and transforming growth factor beta receptor signaling pathway. Located in extracellular space. Is expressed in several structures, including central nervous system; genitourinary system; limb; liver; and lung. Orthologous to human WFIKKN2 (WAP, Follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Wfikkn2 Products (1)

mRNA Protein Name
NM_181819.2 NP_861540.2 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12595574 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within muscle cell development IMP
IMP: Inferred from mutant phenotype
24019467 MGI
acts upstream of or within negative regulation of DNA binding IDA
IDA: Inferred from direct assay
24019467 MGI
acts upstream of or within negative regulation of protein binding IDA
IDA: Inferred from direct assay
24019467 MGI
acts upstream of or within roof of mouth development IGI
IGI: Inferred from genetic interaction
24019467 MGI
acts upstream of or within skeletal system development IGI
IGI: Inferred from genetic interaction
24019467 MGI
acts upstream of or within transforming growth factor beta receptor signaling pathway IDA
IDA: Inferred from direct assay
12595574 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
24019467 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
12595574 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

  • GASP-1

  • growth and differentiation factor-associated serum protein 1

  • mGASP-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15812 WFIKKN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21268 Wfikkn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27786 Wfikkn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wfikkn2 NCBI NCBI:124857