Amelx - amelogenin, X-linked Gene

Also Known as Amel; LRAP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29160

Summary

Enables identical protein binding activity. A structural constituent of tooth enamel. Involved in response to calcium ion; response to nutrient; and response to xenobiotic stimulus. Located in Golgi apparatus; endocytic vesicle; and extracellular matrix. Biomarker of autosomal dominant hypocalcemia. Human ortholog(s) of this gene implicated in amelogenesis imperfecta and amelogenesis imperfecta type 1E. Orthologous to several human genes including AMELX (amelogenin X-linked). [provided by Alliance of Genome Resources, Apr 2022]

Amelx Products (7)

mRNA Protein Name
NM_001271073.1 NP_001258002.1 amelogenin, X isoform isoform 2 precursor
NM_001271074.1 NP_001258003.1 amelogenin, X isoform isoform 1 precursor
NM_001271075.1 NP_001258004.1 amelogenin, X isoform isoform 3 precursor
NM_001271076.1 NP_001258005.1 amelogenin, X isoform isoform 4 precursor
NM_001271077.1 NP_001258006.1 amelogenin, X isoform isoform 6 precursor
NM_001271078.1 NP_001258007.1 amelogenin, X isoform isoform 7 precursor
NM_019154.2 NP_062027.1 amelogenin, X isoform isoform 5 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IDA
IDA: Inferred from direct assay
16674699 RGD
enables structural constituent of tooth enamel IDA
IDA: Inferred from direct assay
16674699 RGD
Biological Process GO Annotation Evidence References Source
involved in response to calcium ion IEP
IEP: Inferred from expression pattern
15721149 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
12667550 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16461365 RGD
Cellular Component GO Annotation Evidence References Source
located in endocytic vesicle IDA
IDA: Inferred from direct assay
10550615 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amelogenin, X isoform

  • amelogenin X chromosome

  • leucine-rich amelogenin peptide

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00647 AMELX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19982 Amelx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26486 Amelx Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amelx NCBI NCBI:265