Tyrp1 - tyrosinase-related protein 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 298182

Summary

Predicted to enable protein homodimerization activity and Tyrosinase activity. Predicted to be involved in melanocyte differentiation; melanosome organization; and positive regulation of melanin biosynthetic process. Predicted to act upstream of or within acetoacetic acid metabolic process; melanin metabolic process; and pigmentation. Predicted to be located in clathrin-coated endocytic vesicle membrane; endosome membrane; and melanosome membrane. Predicted to be active in melanosome. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (Tyrosinase related protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tyrp1 Products (1)

mRNA Protein Name
NM_001106664.1 NP_001100134.1 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor
Protein Preferred Names Protein Names

5,6-dihydroxyindole-2-carboxylic acid oxidase

  • tyrosine phosphatase 1, same as B (Brown)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99622 Flanvotumab Inhibitor ≥99.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N6069 Raspberry ketone glucoside Activator 99.52% Unkown
HY-RS15310 TYRP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-161612 Mycosporine 2 glycine Inhibitor / Unkown
HY-RS18847 Tyrp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25339 Tyrp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990149 Anti-Mouse/Human TYRP1 Antibody (TA99) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tyrp1 NCBI NCBI:7306