Pik3cg - phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Gene

Rattus norvegicus

Also known as Pi3k

Gene ID: 298947 | Gene type: protein coding

About Pik3cg

Primary_assembly 6: 48,766,864-48,802,043 reverse strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 215 orthologues, 9 paralogues and is associated with 40 phenotypes. Biased expression in Thymus (RPKM 145.7), Spleen (RPKM 18.5) and 8 other tissues.

Summary

Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including hepatocyte apoptotic process; negative regulation of triglyceride catabolic process; and phosphatidylinositol phosphate biosynthetic process. Part of phosphatidylinositol 3-kinase complex. Used to study liver cirrhosis. Biomarker of diabetic retinopathy. Human ortholog(s) of this gene implicated in autistic disorder and swine influenza. Orthologous to human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Pik3cg Products(1)

mRNA	Protein	Name
NM_001371300.2	NP_001358229.1	phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

Pik3cg Protein Structure

PIK3CG_ABD

PI3K_rbd

C2_PI3K_class_I_gamma

PI3Ka_I

PI3Kc_IB_gamma

0
200
400
600
800
1000
1102 a.a.

Protein Preferred Names

Protein Names

phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

phosphoinositide-3-kinase, catalytic, gamma polypeptide

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS10532	PIK3CG Human Pre-designed siRNA Set A	/	Unkown
HY-RS10533	Pik3cg Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS10534	Pik3cg Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pik3cg	NCBI	NCBI:5294

Name
Email *

	Sorry, but the email address you supplied was invalid.