PIK3CG
The p110γ catalytic subunit, encoded by PIK3CG, distinguishes class IB PI3K from the class IA enzymes: it associates with the p101 or p84 regulatory subunit and is activated principally by Gβγ subunits released from G protein-coupled receptors rather than by tyrosine kinase receptors. Its expression is concentrated in leukocytes, platelets and heart. p110γ governs neutrophil and macrophage chemotaxis, mast-cell responses and T-cell trafficking, and it modulates cardiac contractility and maladaptive remodeling under stress, making it a dual target of interest for inflammatory disease and heart failure research. Genetic deletion studies in mice confirm its dominant role in directing leukocyte recruitment to sites of inflammation.
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PIK3CG Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
