Act5C - Actin 5C Gene

Also Known as A; A4V404_DROME; Ac5C; act; Act; ACT; act 5C; Act-5C; ACT1_DROME; Act5; act5C; Act5c; ACT5C; actin; Actin; Actin/BAP47; actin5C; Actin5C; actomyosin; anon-EST:fe2D2; ArpA; Bap47; BAP47; beta-actin; beta-Actin; beta-actin/Bap47; CG4027; chrX:5748184..57483

Species: Drosophila melanogaster (fruit fly)

Gene Type: protein coding
Gene ID: 31521

Summary

Involved in several processes, including maintenance of protein location in cell; mitotic cytokinesis; and sperm individualization. Part of Ino80 complex and brahma complex. Is expressed in several structures, including circulatory system; embryonic/larval midgut; ganglia; gonad; and presumptive embryonic/larval system. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20. Orthologous to human ACTB (actin beta) and ACTG1 (actin gamma 1). [provided by Alliance of Genome Resources, Apr 2022]

Act5C Products (1)

mRNA Protein Name
NM_078497.4 NP_511052.1 actin 5C, isoform B [Drosophila melanogaster]

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in maintenance of protein location in cell IMP
IMP: Inferred from mutant phenotype
16174742 FlyBase
involved in mitotic cytokinesis IMP
IMP: Inferred from mutant phenotype
16174742 FlyBase
involved in ovarian fusome organization IEP
IEP: Inferred from expression pattern
9344535 FlyBase
involved in sperm individualization IEP
IEP: Inferred from expression pattern
12642486 FlyBase
involved in tube formation IGI
IGI: Inferred from genetic interaction
25233220 FlyBase
Cellular Component GO Annotation Evidence References Source
part of Ino80 complex IDA
IDA: Inferred from direct assay
16618800 FlyBase
part of brahma complex IDA
IDA: Inferred from direct assay
15060132 FlyBase
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

actin 5C

  • 5C actin

  • Act5C-PA

  • Act5C-PB

  • Act5C-PC

  • Act5C-PD

  • Act5C-PE

  • CG4027-PA

  • CG4027-PB

  • CG4027-PC

  • CG4027-PD

  • CG4027-PE

  • Dm-actin5C

  • F-actin

  • G-actin

  • actin

  • actin 5 C

  • actin 5c

  • actin A1

  • actin5C

  • anon-fast-evolving-2D2

  • beta-actin

  • cellular cytoskeletal beta-

Act5C Antibodies

Cat. No. Product Name Application Reactivity
HY-P81254 Beta Actin (Fruit Fly) Antibody WB Fruit Fly