Nlrx1 - NLR family member X1 Gene

Also Known as RGD1311293

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315599

About Nlrx1

Primary_assembly 8: 44,590,048-44,606,484 reverse strand.mRatBN7.2:CM026981.1

This gene has 1 transcript (splice variant), 193 orthologues, 21 paralogues and is associated with 8 phenotypes. Biased expression in Muscle (RPKM 8.1), Kidney (RPKM 6.) and 9 other tissues.

Summary

Predicted to enable ATP binding activity. Predicted to be involved in intracellular signal transduction and negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within negative regulation of cytokine production and negative regulation of defense response. Predicted to be located in cell junction and plasma membrane. Predicted to be active in mitochondrion. Orthologous to human NLRX1 (NLR family member X1). [provided by Alliance of Genome Resources, Apr 2022]

Nlrx1 Products (1)

mRNA Protein Name
NM_001025010.1 NP_001020181.1 NLR family member X1 precursor

Nlrx1 Protein Structure

P-loop_NTPase

P-loop_NTPase: cl38936 (157 - 317)

PPP1R42

PPP1R42: cl42388 (695 - 900)

LRR_RI

LRR_RI: sd00033 (695 - 723)

LRR_RI

LRR_RI: sd00033 (724 - 745)

LRR_RI

LRR_RI: sd00033 (746 - 769)

LRR_RI

LRR_RI: sd00033 (770 - 805)

LRR_RI

LRR_RI: sd00033 (806 - 833)

LRR_RI

LRR_RI: sd00033 (862 - 883)

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  • 973 a.a.
Protein Preferred Names Protein Names

NLR family member X1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-141521 Amelenodor Activator / Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-CE00479 (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA Modulator / Unkown
HY-RS09365 NLRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09366 Nlrx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09367 Nlrx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-148285 Succinyl CoA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nlrx1 NCBI NCBI:79671