Nlrx1 - NLR family member X1 Gene

Rattus norvegicus

Also known as RGD1311293

Gene ID: 315599 | Gene type: protein coding

About Nlrx1

Primary_assembly 8: 44,590,048-44,606,484 reverse strand.mRatBN7.2:CM026981.1

This gene has 1 transcript (splice variant), 193 orthologues, 21 paralogues and is associated with 8 phenotypes. Biased expression in Muscle (RPKM 8.1), Kidney (RPKM 6.) and 9 other tissues.

Summary

Predicted to enable ATP binding activity. Predicted to be involved in intracellular signal transduction and negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within negative regulation of cytokine production and negative regulation of defense response. Predicted to be located in cell junction and plasma membrane. Predicted to be active in mitochondrion. Orthologous to human NLRX1 (NLR family member X1). [provided by Alliance of Genome Resources, Apr 2022]

Nlrx1 Products(1)

mRNA	Protein	Name
NM_001025010.1	NP_001020181.1	NLR family member X1 precursor

Nlrx1 Protein Structure

P-loop_NTPase

PPP1R42

LRR_RI

0
200
400
600
800
973 a.a.

Protein Preferred Names

Protein Names

NLR family member X1

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-141521	Amelenodor	Activator	98.47%	Phase 1

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS09365	NLRX1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS09366	Nlrx1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS09367	Nlrx1 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nlrx1	NCBI	NCBI:79671

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