Fstl4 - follistatin-like 4 Gene

Also Known as SPIG1; mKIAA1061; B230374F23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320027

Summary

Enables brain-derived neurotrophic factor binding activity. Acts upstream of or within negative regulation of brain-derived neurotrophic factor receptor signaling pathway; negative regulation of collateral sprouting; and negative regulation of dendritic spine development. Located in secretory granule. Is expressed in medulla oblongata basal plate mantle layer; neural retina; olfactory cortex mantle layer; pons mantle layer; and telencephalon mantle layer. Orthologous to human FSTL4 (Follistatin like 4). [provided by Alliance of Genome Resources, Apr 2022]

Fstl4 Products (1)

mRNA Protein Name
NM_177059.4 NP_796033.2 follistatin-related protein 4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables brain-derived neurotrophic factor binding IDA
IDA: Inferred from direct assay
24573299 MGI
Biological Process GO Annotation Evidence References Source
NOT acts upstream of or within negative regulation of axon extension IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within negative regulation of brain-derived neurotrophic factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within negative regulation of collateral sprouting IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within negative regulation of dendritic spine development IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within regulation of collateral sprouting IGI
IGI: Inferred from genetic interaction
24573299 MGI
Cellular Component GO Annotation Evidence References Source
located in secretory granule IDA
IDA: Inferred from direct assay
24573299 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

follistatin-related protein 4

  • follistatin-like protein 4

  • m-D/Bsp120I 1-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05130 FSTL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22517 Fstl4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29038 Fstl4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fstl4 NCBI NCBI:23105